Irreversible vagina antibiosis gel preparation and preparation method thereof

Abstract

The invention discloses an irreversible vagina antibiosis gel preparation and a preparation method thereof. The vagina antibiosis gel preparation will not decrease the gel solidifying strength following the change of season or temperature. In 100ml gel preparation, the raw materials comprise 0.5 to 39.5 g chitosan, 1.5 to 23.5 g dried scallop flavor powder, 0.5 to 4.5 g wormwood flavor powder, 0.5 to 3.5 g cool gel, 0.5 to 2.5 g gelatin, and balance of purified water. The preparation method thereof comprises the steps of: mixing the raw materials in proportion, adding in purified water till reaching the required quantity, regulating ph value ranged between 5.0 and 7.0 by using acid-base regulating agent, preparing irreversible gel, and then standing by for a whole night. The vagina antibiosis gel preparation of the invention has the functions of cleaning and nursing the vagina and cervix uteri of adult women and preventing the pathological changes. After the antibiosis gel is put into the vagina, the gel will uniformly distribute on the vagina mucosa and the cervix uteri so as to kill pathopoiesia microorganisms for a long time and restrain the growing of cancer cell, lubricate the vagina and perform anti-infection and repairing functions.

Description

technical field [0001] The invention relates to an irreversible vaginal antibacterial gel preparation and a preparation method thereof. Background technique [0002] Gynecological inflammation is a frequently-occurring disease that plagues adult women, specifically including female vulvitis, vaginitis, cervicitis, pelvic inflammatory disease, etc., with symptoms such as itching, odor, pain, and abnormal urination in the private parts. If it is not scientifically examined in time or treated inappropriately, it will develop into cervical invasive cancer. The incidence of cervical lesions and uterine cancer has also become younger in recent years, and it is also a helpless choice for most women who have undergone hysterectomy. Statistics show that the incidence rate of adult women is as high as 80% in rural areas, and 64% in small and medium cities. ; About 60% of women take 3-6 days a month to treat reproductive tract infections. Gynecological inflammation is very harmful a...

AI Technical Summary

Problems solved by technology

[0003] The early treatment of gynecological inflammation usually uses lotion. While killing harmful bacteria, the lotion will also kill the beneficial vaginal bacteria and destroy the balance environment in the vagina. Long-term use will greatly reduce the local resistance. Increase the chance of re-infection with germs; people with severe inflammation take more medicines, and the main ingredients of oral medicine dosage forms are Chinese and Western medicines, which are absorbed by the stomach and cause great harm to the body, especially liver and kidney damage, and the onset time is slow. The mechanism of action is The medicine enters the vagina through the blood circulation and kills the bacteria. Generally, long-term use is required to show curative effect, and the side effects are strong; local medicine is preferred for the treatment of gynecological inflammation: (1) traditional suppositories and membranes: they are composed of single or multi-flavored Chinese medicines Composition, poor penetration, incomplete absorption, severe drug loss, no adhesion, relatively fast onset time, drug enters and sterilizes through the vagina, short-term effect is good, some drugs will enter the blood and be lost, such as extrusion type (2) Gel dosage form: usually a liquid applicator made of high-density polyethylene material (HDPE), the gel is directly pushed into the affected area, and the drug does not Participate in blood circulation, take effect quickly, without any side effects

However, the gel is susceptible to changes in seasons or temperatures and reduces the coagulation strength, resulting in a lot of loss and odor, which directly affects the adhesion and therapeutic effect of the gel.