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Novel antihypertensive drug

A technology of high blood pressure and compound preparations, which is applied in the field of medicine, can solve the problems of affecting the efficacy of drugs, inaccurate clinical dosage, and increased side effects, and achieve the effect of improving the antihypertensive effect, less adverse reactions, and good antihypertensive effect

Inactive Publication Date: 2010-06-30
JIANGSU JIBEIER PHARMA
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0016] The product of the present invention overcomes that when felodipine and metoprolol are used clinically, the drug dose is increased to ensure the curative effect when a single drug is used alone, resulting in a significant increase in side effects; , and the use of inaccurate clinical dosages affects the defects of drug efficacy

Method used

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  • Novel antihypertensive drug
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Embodiment 1

[0033] A compound preparation containing the following components:

[0034] Felodipine 5mg

[0035] Metoprolol 50mg

[0036] Starch 40mg

[0037] Calcium Sulfate 20mg

[0038] Talc 2mg

[0039] Silica 1.5mg

[0040] Carboxymethyl Starch Sodium 2mg

[0041] Magnesium stearate 0.5mg

[0042] This embodiment can be made into compound felodipine-metoprolol tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

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Abstract

The invention discloses a compound preparation for curing hypertension, which includes 2-10mg of felodipine and 5-50mg of metoprolol. The invention provides a novel compound preparation which solves the problem that when only one of felodipine and metoprolol is used clinically, in order to ensure the curative effect, the dosage of the drug is increased, which leads to obvious increase of the side effects. Felodipine and metoprolol are used together, so synergic and complementary curative effect can be produced. The novel antihypertensive drug enhances the tolerance of the patient, improves the compliance and reduces the dosage and the adverse reaction, and is convenient to take and cheap in price.

Description

technical field [0001] The invention relates to the technical field of medicine and discloses a medicine for treating hypertension. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. In 1991, my country conducted a sample survey of 940,000 people over the age of 15. Statistics show that the prevalence of hypertension in my country has reached 11.26%, which is 25% higher than that in the 10 years from 1979 to 1980. There are more than 1.3 patients with hypertension in my country. 100 million. Moreover, this upward momentum continues. Statistics also show that the treatment rate of hypertension is 17.4% in urban areas and 5.4% in rural areas; the control rate (systolic blood pressure<140mmHg and diastolic blood pressure<90mmHg after treatment) is only 2.9%. From the above statistics, it can be seen that the prevalence of hypertension in my country is constantly increasing, but the treatment ...

Claims

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Application Information

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IPC IPC(8): A61K31/4422A61K31/138A61P9/12
Inventor 陆梅吴修艮陈进高瑞银聂丽云
Owner JIANGSU JIBEIER PHARMA
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