Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for synthesizing polysantalol

A technology of polysantalol and synthesis method, applied in chemical instruments and methods, preparation of hydroxyl compounds, preparation of organic compounds, etc., can solve the problems of low reaction yield and complicated operation, achieve high activity and improve reaction yield , Easy to operate effect

Inactive Publication Date: 2010-06-09
SHANGHAI APPLIED TECHNOLOGIES COLLEGE
View PDF0 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current synthetic method of polysantalol is complex in operation and low in reaction yield

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for synthesizing polysantalol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] The present invention is further illustrated below by way of examples.

[0008] Synthesis of Polysantalol: In the first step, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl) is obtained by condensation reaction of bornene aldehyde and butanone -3-penten-2-one; second step, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-3-penten-2- Addition reaction of ketone with methyl iodide to produce 3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-pentene-2- Ketone; the third step, 3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ketone reduction makes poly Sandalol. Its reaction formula is as follows:

[0009]

[0010] a: potassium hydroxide, methanol-water, room temperature, sulfuric acid; b: sodium hydroxide, octadecyltrimethylammonium bromide, toluene, methyl iodide; c: potassium borohydride, ethanol.

[0011] Concrete preparation steps of the present invention:

[0012] The first step: the preparation of 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-y...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for synthesizing polysantalol. The method is divided into the following three steps: 1, condensing brain olefine aldehyde and butanone by adopting potassium hydroxide as a catalyst and aqueous solution of methanol as solvent to prepare 3-methyl-5-(2,2,3-trimethyl-3-cyclopentene-1-base)-3-pentene-2-ketone; 2, subjecting the 3-methyl-5-(2,2,3-trimethyl-3-cyclopentene-1-base)-3-pentene-2-ketone and methyl iodide to addition reaction by adopting octadecyl trimethyl ammonium bromide as the catalyst in order to prepare 3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopentene-1-base)-4-pentene-2-ketone; and 3, reducing the 3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopentene-1-base)-4-pentene-2-ketone by adopting potassium borohydride as a reducing agent so as to prepare the polysantalol. The method has the advantages of easy operation and high reaction yield.

Description

technical field [0001] The present invention relates to the synthesis method of polysantalol. Background technique [0002] Polysantalol is a very important new type of sandalwood fragrance. In addition to the elegant sandalwood aroma, it also has a unique sweet and creamy aroma. It is used in daily chemical essence, beauty care products, laundry care products, household supplies. The current synthetic method of polysantalol is complex in operation and low in reaction yield. Contents of the invention [0003] The present invention aims at above-mentioned problem, provides the synthetic method of polysantalol which is easy to operate and has high reaction yield. [0004] The synthetic method of polysantalol: [0005] In the first step, borneol and butanone are subjected to condensation reaction to obtain 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-3-pentene- 2-ketone, the reaction uses potassium hydroxide as a catalyst, and aqueous methanol as a solvent; the second ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07C33/12C07C29/143
Inventor 章平毅戴晖陆欢沈蔚
Owner SHANGHAI APPLIED TECHNOLOGIES COLLEGE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com