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Chinese medicinal soft capsule for treating gastral cavity pain and preparation method thereof

An epigastric pain, soft capsule technology, applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of inability to guarantee the quality and efficacy of drugs, rough preparation process of the original dosage form, loss of volatile substances, etc. , to achieve the effect of high capsule strength and film occlusion, good appearance gloss, and small drug error.

Inactive Publication Date: 2010-05-12
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Years of clinical application have shown that the original dosage form has good clinical efficacy, but there are two shortcomings: one is that the original dosage form is completely expressed in traditional Chinese medicine terms, and it does not explain what disease to treat in combination with Western medicine, which has brought certain limitations to the promotion of the drug. It is actually used in the treatment of various stomach diseases, such as epigastric pain, belching, acid regurgitation, fullness, coronary heart disease and angina pectoris, chest pain, chest tightness, shortness of breath, palpitations, etc. High, at the same time in this technology, Daguomu ginger and borneol contain a large amount of volatile substances, using ordinary hard capsules, the sealing is poor, resulting in a large loss of volatile substances, and the quality and curative effect of the medicine cannot be guaranteed

Method used

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  • Chinese medicinal soft capsule for treating gastral cavity pain and preparation method thereof
  • Chinese medicinal soft capsule for treating gastral cavity pain and preparation method thereof
  • Chinese medicinal soft capsule for treating gastral cavity pain and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0291] Example 1: Weigh 300 g of Rhizoma Macrocarpa ginger and 50 g of Ai tablets. Take moxa flakes, crush, pass through a 120-mesh sieve, and set aside; add 3 times the amount of water, soak for 3 hours, distill and extract for 8 hours; take the volatile oil, set aside; take 316g soybean oil and 16g beeswax, heat and melt, and cool until After room temperature, add volatile oil and 50 g of moxa tablets to mix uniformly, grind with a colloid mill for 15 minutes, and press to make 1000 granules to obtain the soft capsule of the present invention. This product is 0.4g per capsule, orally, 1 capsule at a time, 3 times a day, 7 days as a course of treatment; take it before or during meals.

Embodiment 2

[0292] Example 2: Weigh 300 g of Rhizoma Macrocarpa ginger and 50 g of Moxa tablets. Take moxa flakes, crush, pass through a 120-mesh sieve, and set aside; take the supercritical CO 2 Extract the volatile oil for use; take 320 g of soybean oil, 20 g of beeswax, heat and melt, cool to room temperature, add volatile oil and 50 g of moxa tablets, mix uniformly, grind with a colloid mill for 15 minutes, and press to make 1000 capsules to obtain the soft capsule of the present invention. This product is 0.4g per capsule, orally, 1 capsule at a time, 3 times a day, 7 days as a course of treatment; take it before or during meals.

Embodiment 3

[0293] Example 3: Weigh 150g of the raw material medicinal material Daguomu ginger and 25g of Ai tablets. Take moxa flakes, smash, pass through a 120 mesh sieve, and set aside; add 3 times the amount of water, soak for 3 hours, distill and extract for 8 hours; take the volatile oil and use it for later use; take 158 g of soybean oil and 8 g of beeswax, heat and melt, and cool until After room temperature, add volatile oil and 25 g of moxa tablets to mix uniformly, grind with a colloid mill for 15 minutes, and press to form 500 capsules to obtain the soft capsule of the present invention. This product is 0.4g per capsule, orally, 1 capsule at a time, 3 times a day, 7 days as a course of treatment; take it before or during meals.

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Abstract

The invention discloses a Chinese medicinal soft capsule for treating gastral cavity pain and a preparation method thereof. The soft capsule is prepared from 75 to 95 weight percent of litsea lancilimba, 5 to 25 weight percent of blumea camphor and appropriate amount of auxiliary materials. The Chinese medicinal soft capsule has the effects of promoting qi circulation and relieving pain, and is mainly used for treating symptoms such as gastral cavity pain, acid regurgitation during belching, tumescence, stethalgia, chest distress, short breath, palpitation and the like which are caused by qi stagnancy and blood stasis. The original stomach analgesic capsules are changed into the soft capsule preparations; and the Chinese medicinal soft capsule has improved stability and curative effect, accurate contents of the medicaments, beautiful appearance, high purity, little administration dosage, high bioavailability, stable quality, good curative effect and good safety.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine soft capsule for treating gastric cavity pain and a preparation method thereof, and belongs to the technical field of medicines. Background technique [0002] Stomach pain, also known as epigastric pain, is a disease mainly caused by pain in the epigastric cavity near the heart. The "heartache" and "heartache" in the literature of the past dynasties mostly refer to stomachache. For example, "Su Wen. Liu Yuan Zheng Ji Da Lun" said: "Beware of stomach pain and pain in people's diseases." "Medical Zheng Chuan" said: "Nine kinds of heartache in ancient prescriptions.... The reasons are all in the stomach, and It’s not about the heart.” Stomach pain is a common clinical symptom. It is more common in acute and chronic gastritis, gastric and duodenal ulcers, and gastric nervosa. It is also seen in diseases such as gastric mucosal prolapse, gastroptosis, pancreatitis, cholecystitis and cholelithiasis. Stoma...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61K9/48A61P1/04
Inventor 师红毅
Owner GUIZHOU YIBAI PHARMA CO LTD
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