Glucosamine chewable tablet used for relieving and preventing osteoarthritis and preparation method thereof

Abstract

The invention discloses a glucosamine chewable tablet used for relieving and preventing osteoarthritis and a preparation method thereof. The glucosamine chewable tablet comprises active ingredients and auxiliary materials, wherein the active ingredients comprise glucosamine, vitamin C and dimethyl sulfone, the glucosamine is glucosamine sulfate or glucosamine hydrochloride or glucosamine phosphateor mixture of the glucosamine sulfate and the glucosamine hydrochloride and the glucosamine phosphate; and the auxiliary materials comprise excipient, bonding agent, flavouring agent and lubricant. The glucosamine chewable table is slowly disintegrated and released without entering the gastrointestinal tract through the chewing and is absorbed through the increment of the taking number, therefore, the medicine effect is improved, and the discomfort of a patient with poor gastrointestinal tract function, caused by a deglutible tablet accelerating the gastrointestine load, is reduced. The glucosamine chewable tablet has the advantages of good mouth feel, high bioavailability, more convenient taking, convenient carrying and the like, and can fully play a role of the product.

Description

technical field [0001] The invention belongs to the technical field of glucosamine medicine and health care products, and in particular relates to a glucosamine chewable tablet for alleviating and preventing osteoarthritis and a preparation method thereof. Background technique [0002] Treatment methods for osteoarthritis include drug therapy, surgery, physical therapy, physical therapy and other adjuvant treatments. Among them, drug therapy is the most widely used, and non-steroidal drugs are currently the most commonly used drugs for the treatment of osteoarthritis clinically, including ibuprofen, diclofenac, meloxicam, nebumetone, etc. Although this drug is effective in reducing symptoms, it is not a drug for the cause of osteoarthritis. The mechanism of action of non-steroidal anti-inflammatory drugs is mainly to achieve anti-inflammatory and analgesic effects by inhibiting cyclooxygenase. However, the side effects of non-steroidal anti-inflammatory drugs are also obvio...

AI Technical Summary

Problems solved by technology

However, the current glucosamine hydrochloride is generally an oral gastric-soluble swallowable preparation. The drug cannot be absorbed quickly, the onset of effect is slow, and it is inconvenient to take. Especially for the elderly and patients with dysphagia, ordinary tablets are often difficult to take. , aggravate the gastrointestinal burden and cause discomfort, and long-term medication may even lead to psychological drug resistance

In addition, because the drug needs to be slowly disintegrated and released when it reaches the gastrointestinal tract, the bioavailability of glucosamine in the human body is not high