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Chinese medicine compound for controlling chronic pelvic inflammation

A technology of chronic pelvic inflammatory disease and composition, which is applied in the directions of drug combination, sexual diseases, medical formula, etc., can solve the problem that the effect is not as good as Coptis chinensis

Inactive Publication Date: 2010-02-03
苏州世林医药技术发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Pharmacological action: Phellodendron Phellodendri has similar antibacterial spectrum and antibacterial efficacy to Coptis chinensis, and has inhibitory effect on Shigella, Salmonella typhi, Mycobacterium tuberculosis, Staphylococcus aureus, hemolytic streptococcus and other pathogenic bacteria; Terminal spirochetes and hepatitis B surface antigen also have inhibitory effects; they have protective effects on platelets; external use can promote the absorption of subcutaneous oozing blood; in addition, they also have functions such as promoting choleresis, diuresis, lowering blood pressure, antipyretic, antitussive, and expectorant, but their effects Not as good as coptis

Method used

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  • Chinese medicine compound for controlling chronic pelvic inflammation

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Effect test

Embodiment 1

[0035]Prescription composition: Pulsatilla 25%, Rhizoma Cyperi 25%, Phellodendron 10%, Atractylodes 15%, Achyranthes bidentata 15%, Fructus Cnidii 10%

[0036] Preparation method 1: Pulsatilla chinensis, Phellodendron Phellodendri, and Achyranthes bidentata decoction pieces are extracted twice with 80% ethanol with 10 times the amount, each time for 1.5 hours, the extracts are combined, filtered, concentrated under reduced pressure, and the ethanol is recovered to obtain the alcohol extract extract①; Rhizoma Cyperi, Atractylodes cut into decoction pieces and extracted twice with 8 times the amount of water, 1.5 hours each time, combined extracts, filtered, concentrated under reduced pressure to obtain extract ②, collected volatile oil, combined extract ① and extract ②, added appropriate amount of microcrystalline cellulose and micropowder silica gel, wet granulation by conventional method, dissolve volatile oil with appropriate amount of ethanol, spray evenly on the granules, a...

Embodiment 2

[0040] Pulsatilla 20%, Rhizoma Cyperus 20%, Phellodendron 10%, Atractylodes 10%, Achyranthes bidentata 10%, Cnidium 10%, Atractylodes macrocephala 5%, Flea 5%, Sophora flavescens 10%.

[0041] Preparation method: make decoction pieces from Pulsatilla chinensis, Rhizoma Cyperi, Phellodendron Phellodendron, Atractylodes atractylodes, Cnidium atractylodes, Achyranthes bidentata, and Atractylodes macrocephala in the prescription, extract twice with 80% ethanol with 8-10 times the amount, each time for 1.0-2.0h, filter, and concentrate into an extract ①; the rest of the medicinal materials were pulverized and mixed, and the coarse powder of the medicinal materials was extracted twice with 8 times the amount of water, filtered for 1.5 hours each time, concentrated into an extract ②, combined and concentrated, and made into capsules according to a conventional method.

Embodiment 3

[0043] Prescription composition: Pulsatilla 25%, Rhizoma Cyperi 25%, Cortex Phellodendri 5%, Atractylodes 10%, Achyranthes bidentata 10%, Cnidium 5%, Gentiana 5%, Coix Seed 5%, Toosendan 10%.

[0044] Preparation method: make decoction pieces from Pulsatilla radiata, Rhizoma Cyperi, Phellodendron Phellodendron, Atractylodes atractylodes, Achyranthes bidentata and Fructus Cnidii in the prescription, extract twice with 80% ethanol in 8-10 times, each time for 1.0-2.0h, filter, and concentrate to obtain The extract ①; the rest of the medicinal materials were pulverized and mixed, and the coarse powder of the medicinal materials was extracted twice with 8 times the amount of water, each time for 1.5 hours, filtered, concentrated to obtain the extract ②, combined and concentrated, and made into capsules according to the conventional method.

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Abstract

The invention discloses a Chinese medicine compound taking six Chinese medicines including pulsatilla chinensis, cyperus rotundus, phellodendron, atractylodes, achyranthcs bidentata blume as a basic prescription, and an application thereof on the aspect of controlling chronic pelvic inflammation. Clinical trials confirm that the compound has obvious effects on controlling diseases such as chronicannexitis, chronic cervicitis, cervical erosion, and the like.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and specifically relates to a traditional Chinese medicine composition and its application in the prevention and treatment of chronic pelvic inflammatory disease. Composition of traditional Chinese medicine. Background technique [0002] This prescription is Professor Li Xiaoran's clinical experience prescription, which is taken by the attending woman. Its prescription is derived from clinical practice, unique in legislation, and rigorous in formulating prescriptions. It clears away heat and dampness, soothes the liver and promotes qi, removes blood stasis and detoxifies, and eliminates filth and leukorrhagia. Its manifestations are increased leukorrhagia, long-term treatment, thin or sticky mass, white or yellowish turbidity, dull pain in the lower abdomen, short red urine, or accompanied by vulvar itching. The indication is chronic pelvic inflammatory disease. Clinically, the main symptoms ...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61K36/8994A61K36/9066A61P15/00
Inventor 李笑然杨世林许琼明郝丽莉刘艳丽唐丽华游本刚
Owner 苏州世林医药技术发展有限公司
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