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Traditional Chinese medicine combination for treating leukemia and preparation method thereof

A composition, leukemia technology, applied in the direction of drug combination, pharmaceutical formula, active ingredient of hydroxy compound, etc.

Active Publication Date: 2009-12-02
INCREASEPHARM HENGQIN INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there is no unified basis for syndrome differentiation, the general trend of syndrome differentiation in traditional Chinese medicine is still mainly the deficiency of both qi and yin, the deficiency of both qi and blood, the accumulation of heat and toxin, and the stagnation of blood stasis.

Method used

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  • Traditional Chinese medicine combination for treating leukemia and preparation method thereof
  • Traditional Chinese medicine combination for treating leukemia and preparation method thereof
  • Traditional Chinese medicine combination for treating leukemia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Realgar 0.08kg, Qingdai 2kg, Salvia miltiorrhiza 12kg, borneol 0.2kg

[0043] Add 5 times the amount of water, decoct for 2 hours, filter, add 4 times the amount of water to the filter residue, decoct for 1 hour, filter, discard the filter residue, combine the filtrate twice, concentrate the filtrate to 12L under reduced pressure, add ethanol to make the liquid The concentration of alcohol is 70%, let it stand, filter, concentrate to a thick paste with a relative density of 1.30-1.35 (50°C), dry under reduced pressure (60°C, -0.08Mpa), and obtain the extract of Danshen;

[0044] Heat and melt 20kg polyethylene glycol 4000 and 8kg polyethylene glycol 6000, add the fine powder of salvia miltiorrhiza extract, realgar, indigo naturalis, and borneol, mix well, keep warm at 60-80°C, drop into the cooled simethicone, and wait After the dropping pills are cooled, take them out, drain and wipe off the simethicone oil to obtain the dropping pills.

Embodiment 2

[0046] Realgar 0.05kg, Qingdai 2kg, Salvia miltiorrhiza 12kg, borneol 0.2kg

[0047] Add 5 times the amount of water, decoct for 2 hours, filter, add 4 times the amount of water to the filter residue, decoct for 1 hour, filter, discard the filter residue, combine the filtrate twice, concentrate the filtrate to 12L under reduced pressure, add ethanol to make the liquid The concentration of alcohol is 70%, let it stand, filter, concentrate to a thick paste with a relative density of 1.30-1.35 (50°C), dry under reduced pressure (60°C, -0.08Mpa), and obtain the extract of Danshen;

[0048] Crush the salvia miltiorrhiza extract, realgar, Qingdai, and borneol into fine powder, add appropriate amount of honey, mix evenly, and make pills.

Embodiment 3

[0050] Realgar 0.1kg, Qingdai 2kg, Salvia miltiorrhiza 9kg, Borneol 0.2kg

[0051] Radix Radix Radix Radix Radix Radix Radix Radix Ginseng extracts 8 times of amount 70% ethanol, 2 times, each time 1 hour, filters, filter residue is discarded, merges 2 filtrates, reclaims ethanol, concentrates to the thick ointment that relative density is 1.30-1.35 (50 ℃), reduces Press and dry (60°C, -0.08Mpa) to obtain the Danshen extract;

[0052] The salvia miltiorrhiza extract, realgar, Qingdai, and borneol are crushed into fine powder, 10 kg of lactose is added, mixed evenly, granulated with 95% ethanol, dried, and packed into capsules to obtain capsules.

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Abstract

The invention discloses a traditional Chinese medicine combination for treating leukemia and a preparation method thereof. The combination is prepared by realgar, indigo naturalis, salvia miltiorrhiza and borneol according to a certain weight proportioning. The combination can be prepared into any kind of usual dosage form. The traditional Chinese medicine combination of the invention has the functions of clearing heat, detoxicating and invigorating blood circulation and is applied to treating various chronic and acute leukemias.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating leukemia and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Leukemia is a malignant disease of blood-forming tissues. It is characterized by the unlimited proliferation of a large number of leukemia cells in the bone marrow and other hematopoietic tissues, and enters the peripheral blood, while the production of normal blood cells is significantly inhibited. Viruses may be the main pathogenic factor, but there are many factors such as radiation, chemical poisons (benzene, etc.) or drugs, genetic quality, etc. may be pathogenic cofactors. According to the degree of immaturity of leukemia cells and the natural course of leukemia, it is divided into two categories: acute and chronic. According to the type of proliferating cells, it can be divided into three types: granulocytic, lymphocytic and monocytic. ...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61K36/70A61K9/20A61K9/48A61P35/02A61K31/045A61K33/36
Inventor 胡杰
Owner INCREASEPHARM HENGQIN INST CO LTD
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