Soluble compound doxycycline hyclate powder for animals and preparation method thereof
A doxycycline hydrochloride, soluble technology, applied in the direction of tetracycline active ingredients, medical preparations containing active ingredients, powder delivery, etc. The effect of relieving the body's stress response, increasing the rate of weight gain, and reducing the chance of drug resistance
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Embodiment 1
[0018] (1) Pass doxycycline hydrochloride, ofloxacin, and anhydrous glucose through a 24# sieve respectively, and set aside.
[0019] (2) Weigh 1 kg of sieved doxycycline hydrochloride, 5 kg of ofloxacin and 5 kg of aminophylline and fully mix them in a V-shaped mixer for 30 minutes.
[0020] (3) Add 89 kg of sieved anhydrous glucose into the mixture of the above-mentioned doxycycline hydrochloride, ofloxacin and aminophylline, fully mix in a common mixer for 30 minutes, discharge, and pass 24# Sieve to obtain the compound doxycycline hydrochloride soluble powder of the present invention.
Embodiment 2
[0022] (1) Pass doxycycline hydrochloride, ofloxacin, and anhydrous glucose through a 24# sieve respectively, and set aside.
[0023] (2) Weigh 20 kg of sieved doxycycline hydrochloride, 0.5 kg ofloxacin, and 5 kg of aminophylline and fully mix them in a V-shaped mixer for 30 minutes.
[0024] (3) Add 74.5 kg of sieved anhydrous glucose into the mixture of the above-mentioned doxycycline hydrochloride, ofloxacin and aminophylline, fully mix in a common mixer for 30 minutes, discharge, and pass 24 #Sieve to obtain compound doxycycline hydrochloride soluble powder of the present invention.
Embodiment 3
[0026] (1) Pass doxycycline hydrochloride, ofloxacin, and anhydrous glucose through a 24# sieve respectively, and set aside.
[0027] (2) Weigh 2 kg of sieved doxycycline hydrochloride, 4 kg of ofloxacin and 5 kg of aminophylline and fully mix them in a V-shaped mixer for 30 minutes.
[0028] (3) Add 89 kg of sieved anhydrous glucose into the mixture of the above-mentioned doxycycline hydrochloride, ofloxacin and aminophylline, fully mix in a common mixer for 30 minutes, discharge, and pass 24# Sieve to obtain the compound doxycycline hydrochloride soluble powder of the present invention.
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