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Pharmaceutical composition with pure plant origin and application thereof

A composition and pure plant technology, applied in the direction of drug combination, plant raw materials, medical preparations containing active ingredients, etc., can solve problems such as single treatment link, lack of quality control, and unclear curative effect

Inactive Publication Date: 2012-09-05
中北科技集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But these patents also generally have the disadvantages of the plant compound recommended on overseas professional websites for acne treatment
[0006] To sum up, the current anti-acne products on the market generally have many problems such as single treatment link, obvious side effects, unclear curative effect, long treatment course or lack of stable and effective quality control, etc., which are difficult to meet the needs of domestic and foreign markets.

Method used

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  • Pharmaceutical composition with pure plant origin and application thereof
  • Pharmaceutical composition with pure plant origin and application thereof
  • Pharmaceutical composition with pure plant origin and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0131] Weigh 600kg of salvia miltiorrhiza, 100kg of licorice, and 300kg of loquat leaves, crush them into coarse powder, heat and reflux with 10 times the amount of 80% ethanol at 70°C for 2 hours, filter, and heat and reflux the dregs with 10 times the amount of 80% ethanol Extract for 1 hour, combine the filtrate, concentrate under reduced pressure, and dry the concentrated solution under reduced pressure to obtain 240 kg of dry extract; wherein the content of cryptotanshinone is 0.57% by weight, the content of liquiritin is 0.32% by weight, and the content of ursolic acid It is 0.82% by weight.

Embodiment 2

[0133] Weigh 1000kg of Danshen medicinal material powder, heat and reflux extract with 6 times the amount of 95% ethanol at 70°C for 2 hours, filter, and then use 6 times the amount of 95% ethanol to heat and reflux extract for 1 hour, combine the filtrates, concentrate under reduced pressure, and The concentrate was dried under reduced pressure to obtain 89 kg of dry extract, wherein the content of cryptotanshinone was 1.5%.

Embodiment 3

[0135] Weigh 1000kg of Danshen medicinal material powder, extract by cold immersion in 6 times the amount of 70% ethanol for 2 hours, extract, filter, and repeat the extraction three times, combine the filtrate, concentrate under reduced pressure, and dry the concentrated solution under reduced pressure to obtain 50kg of dry extract. Tanshinone content is 3.6%.

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PUM

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Abstract

The invention provides a pharmaceutical composition with a pure plant origin and application thereof. Pharmacological studies show that the medicament can treat acne from multiple aspects and ensure that propionibacterium acnes do not generate drug resistance. Clinical experiment shows that the medicament has quick response, can cure the acne in a short time, obviously reduces the recurrence, hasgood safety and does not have obvious adverse reaction. Compared with single use of a tanshinone extract (such as a tanshinone capsule), the medicament reduces the dosage, improves the treatment effect and avoids the allergic reaction, such as rash, lip rash and the like. Simultaneously the quality of the medicament and the stability of the healing efficacy are ensured by effectively controlling active ingredients.

Description

technical field [0001] The invention relates to a medicinal composition derived from pure plants and its application, which belongs to the application field of modern herbal medicines. Background technique [0002] Acne (Acne), commonly known as "acne" or "acne", is a common inflammatory skin disease in adolescence. It tends to occur on the face, and the disease period is long and easy to recur. If it is not treated actively, it is easy to leave pigmentation or scars, which will have a serious impact on the patient's appearance and even mental health, and even affect the patient's life, study and work. The disease has a high incidence rate, and the domestic and foreign markets have a large demand for effective therapeutic drugs. [0003] Research suggests that the pathogenesis of the disease is that the hair follicles on the surface of the skin are clogged with oil and dead skin cells, creating excellent conditions for the growth of microorganisms in the hair follicles, esp...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61K36/804A61K36/815A61K36/8968A61K36/8969A61P17/10A61K127/00A61K125/00
Inventor 钟忠谢忱
Owner 中北科技集团股份有限公司
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