Application of imatinib mesylate in preparing drugs used for building congenital cataract animal model
A technology of imatinib mesylate and congenital cataracts, which is applied in the new application field of drugs, can solve the problems of imatinib mesylate that have not yet been seen, and achieve a short cycle, low cost, and high molding rate. Effect
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[0016] The application and effect of imatinib mesylate in the preparation of drugs for establishing animal models of congenital cataract will be described in detail below with reference to the accompanying drawings.
[0017] 1. Experimental animals and materials
[0018] Clean-grade BABL / c mice on the 8th day of birth were purchased from the Animal Center of the Third Military Medical University of the Chinese People's Liberation Army; imatinib mesylate capsules were purchased from Novartis Pharmaceuticals Co., Ltd., Switzerland. Dissolve in distilled water to make a solution with a concentration of 100 mg / mL, and store at 4°C for later use.
[0019] 2. Experimental method
[0020] The clean-grade BABL / c mice on the 8th day of birth were randomly divided into two groups: the experimental group and the control group, and the experimental group was given a concentration of Imatinib mesylate solution of 100 mg / mL was administered continuously for 3 days; the control group was g...
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