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Application of Kegan Liyan Oral Liquid in preparing Chinese medicaments for preventing and treating bird flu

A technology for avian influenza and pharyngeal oral liquid, which is applied in the field of medicine and can solve the problems of no obvious effect and the like

Active Publication Date: 2009-10-28
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although people such as Wang Guoxia reported that the honeysuckle extract had the effect of inhibiting the replication of avian influenza virus in vitro at 3.9mg / ml (that is, every milliliter was equivalent to 3.9mg of crude drug) (Wang Guoxia et al. Experimental research, Journal of Chinese Veterinary Medicine, 2005, No. 3, pages 4-6), but the inventor's research shows that honeysuckle unilaterally has no significant effect on the prevention and treatment of avian influenza in vivo

Method used

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  • Application of Kegan Liyan Oral Liquid in preparing Chinese medicaments for preventing and treating bird flu
  • Application of Kegan Liyan Oral Liquid in preparing Chinese medicaments for preventing and treating bird flu
  • Application of Kegan Liyan Oral Liquid in preparing Chinese medicaments for preventing and treating bird flu

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Embodiment Construction

[0019] 1. Test drugs

[0020] Keganliyan Oral Liquid is produced by Guangzhou Wanglaoji Pharmaceutical Co., Ltd., and the production batch number is 080404. Concrete preparation method is made up of the following steps:

[0021] (1) get honeysuckle 72g, nepeta 72g, windproof 43g and peppermint 43g to extract volatile oil with steam distillation, and the distilled aqueous solution is collected in another device;

[0022] (2) Take 72 g of Scutellaria baicalensis and add 65% (v / v) ethanol to extract twice, each time for 2 hours, recover ethanol, add an appropriate amount of water to boil, filter while hot, and use the filtrate for later use;

[0023] (3) The dregs of step (2) Scutellaria baicalensis extracted with ethanol and the dregs of step (1) honeysuckle, nepeta, windproof and peppermint extracting volatile oil, gardenia 72g, forsythia 72g, scrophulariaceae 72g, silkworm 43g , Rehmannia glutinosa 108g, Shegan 22g, bellflower 43g, cicada slough 43g and licorice 22g, add wat...

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Abstract

The invention relates to application of Kegan Liyan Oral Liquid in preparing Chinese medicaments for preventing and treating bird flu. The Kegan Liyan Oral Liquid is a prepared Chinese patent medicament which is formally approved by the country to be produced and came on the market, and the Chinese Medicine Approval Number of the Kegan Liyan Oral Liquid is Z10970100. The Kegan Liyan Oral Liquid is prepared by mixing the effective compositions prepared by the following raw medicaments, and proper polysorbate 80, stevioside and sodium benzoate, and adding water into the mixture until deionized water is 1,000ml: 72 grams of honeysuckle, 72 grams of baikal skullcap root, 72 grams of schizonepeta tenuifolia, 72 grams of cape jasmine, 72 grams of weeping forsythia, 72 grams of scrophularia ningpoensis, 43 grams of batryticated silkworm, 108 grams of radix rehmanniae, 22 grams of blackberry lily, 43 grams of platycodon grandiflorum, 43 grams of peppermint, 43 grams of cicada slough, 43 grams of saposhnikovia root and 22 grams of liquorice. The Kegan Liyan Oral Liquid can resist bird flu, inhibit mouse pneumonia caused by bird flu, reduce the death rate of bird flu-infected mouse and prolong the survival time of the bird flu-infected mouse, and has obvious function of preventing and treating bird flu.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine for preventing and treating avian influenza. Background technique [0002] Avian influenza is the abbreviation of avian influenza, which is an infectious disease caused by one of the subtypes of influenza A virus (also known as avian influenza virus), and is classified as a Class A infectious disease by the International Office of Epizootics. Avian influenza is mainly transmitted among birds, and occasionally can infect humans. Its clinical manifestations are similar to human influenza, but human avian influenza has severe symptoms, many complications, high fatality rate, and ineffective vaccination. It is somewhat different from ordinary influenza . [0003] The most effective way to prevent and treat influenza at present is to inoculate influenza vaccine, but the avian influenza virus vaccine for clinical application is still not developed so far, thereby increasing the diff...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61K9/00A61P31/16A61P11/00A61K35/64
Inventor 赖小平苏子仁李耿
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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