Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Zedoary turmeric oil adhesive membrane for external application and preparation method thereof

The technology of curcuma curcuma oil and film sticking is applied in the field of curcuma curcuma oil topical film and its preparation, which can solve the problems of inconvenient use and insignificant effect in the treatment of skin diseases, and achieve the effects of improving the antibacterial treatment effect, prolonging the treatment time and improving the treatment effect.

Inactive Publication Date: 2009-10-21
WUHAN UNIV OF TECH
View PDF0 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the dosage forms used or developed include injections, eye drops and suppositories. Although the above-mentioned preparations have certain effects in the treatment of cervical cancer, liver cancer and cardiovascular diseases, they are inconvenient to use for the treatment of skin diseases, and the effect is not good. obvious

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Zedoary turmeric oil adhesive membrane for external application and preparation method thereof
  • Zedoary turmeric oil adhesive membrane for external application and preparation method thereof
  • Zedoary turmeric oil adhesive membrane for external application and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] 1. Preparation of curcuma oil external film

[0013] Dissolve 0.75g of chitosan in 35ml of acetic acid solution with a mass fraction of 2%, and stir to fully dissolve. Add 1.125g of polyvinyl alcohol to 30ml of water, fully dissolve in a constant temperature water bath at 90°C, mix the two solutions evenly, add 1.125g of glycerin, add water to adjust to 100ml, stir evenly, and filter to obtain the filtrate. Add 0.150g zedoary oil to the filtrate, then add 2ml Tween 80, stir while adding, stand still for defoaming after adding, then pour it on a clean polytetrafluoroethylene board, and let it stand in an infrared oven at 30°C for 36 Hours, be careful to form a film, spread the drug film on the non-woven backing layer, and store it in a dry place.

[0014] 2. Content determination

[0015] 1. Determination of Alcohol-oil Coefficient

[0016] Accurately weigh 100mg of turmeric oil, put it in a 10ml volumetric flask, add ethanol to the mark, pipette 0.8ml into a 50ml vol...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
quality scoreaaaaaaaaaa
quality scoreaaaaaaaaaa
Login to View More

Abstract

The invention relates to a zedoary turmeric oil adhesive membrane for external application, which comprises a backing layer and a drug membrane adhered to the backing layer. The drug membrane is prepared by the following steps that: chitosan and an acetic acid solution with the mass fraction of between 0.5 and 5 percent are mixed to prepare a 15 to 25 mg / ml chitosan solution, then the chitosan solution is mixed evenly with a 30 and 40 mg / ml polyvinyl alcohol water solution to obtain a mixed solution, the mass ratio of the chitosan and polyvinyl alcohol is 1: 0.2-1: 5, then glycerol and zedoary turmeric oil are added into the mixed solution, a surfactant is added into the mixed solution, the mixed solution is stirred for 5 to 35 min and is kept stand for defoaming, the membrane spreading is performed, and the drug membrane can be obtained by drying in a baking oven with a temperature of between 20 and 45 DEG C. The adhesive membrane has good sustained control function; the adhesive membrane can be directly pasted on afflicted parts and play a role in positioning; and the adhesive membrane improves the effective concentration of medicaments and prolongs the acting time of the medicaments, improves the bioavailability, furthest reduces the toxic side effect at the same time, and can well play clinical roles of the zedoary turmeric oil in antitumor, skin disease treatment and the like.

Description

technical field [0001] The invention relates to an external application film of zedoary oil and a preparation method thereof. Background technique [0002] Curcuma phaaeocaulis Valeton, C.kwangsiensis S.G.LeeetC.F.Liang and C.wenyujin Y.H.ChenetC.Ling are the dried rhizomes of Zingiberaceae plants. Curcuma zedoary is pungent, bitter, and warm, and returns to the liver and spleen meridian. It has the effects of promoting qi and breaking blood, eliminating accumulation and relieving pain. It is clinically used for lumps in the abdomen, blood stasis, amenorrhea, dyspepsia, distending pain, early cervical cancer, etc. Through in-depth research on the pharmacological activity, mechanism of action, in vivo process, and toxic and side effects of zedoary oil, it is confirmed that zedoary oil has very broad development prospects. Studies have shown that turmeric oil has remarkable effects in anti-tumor and anti-thrombosis, and has anti-early pregnancy, anti-bacterial, liver-protect...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/70A61K47/36A61K47/32A61K47/10A61P17/00A61P35/00A61P17/06A61P31/02A61K125/00
Inventor 刘小平徐莎耿丹清
Owner WUHAN UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com