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Effervescence preparation composition used for sanitary towel and preparation method and application thereof

The technology of an effervescent preparation and composition is applied in the field of effervescent preparation composition and preparation of sanitary napkins, which can solve the problems of inconspicuous drug efficacy of solid preparations and low utilization rate of active substances in liquid preparations, and achieve low loss rate, Efficacy is stable and the effect of avoiding waste of resources

Active Publication Date: 2009-09-02
韩海星
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It uses food-grade raw materials, which are safe and non-toxic, and the preparation adopts powder technology. After the preparation meets water, the acid and alkali in it undergo neutralization reaction to generate gas. The mutual repulsion of the gas accelerates the dissolution rate of the preparation in water, so that the efficacy The ingredients are quickly dissolved, which solves the problem that the efficacy of solid preparations is not obvious, and the problem of low utilization rate of active substances in liquid preparations is improved.

Method used

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  • Effervescence preparation composition used for sanitary towel and preparation method and application thereof
  • Effervescence preparation composition used for sanitary towel and preparation method and application thereof
  • Effervescence preparation composition used for sanitary towel and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0051] The preparation method of a kind of antibacterial effervescent preparation composition provided by the present invention is example, make 1kg:

[0052] Accurately weigh medical PVP, food grade ethanol, sodium bicarbonate, triclosan, soluble starch, malic acid, fumaric acid, sodium lauryl sulfate. The formula is shown in Table 1:

[0053] Table 1: Formula of antibacterial effervescent preparation

[0054] malic acid fumaric acid sodium bicarbonate Medical PVP Triclosan soluble starch Sodium dodecyl sulfate 8.94％ 4.29％ 13.1％ 3.56％ 0.3％ 69.80％ 0.01％

89.4g

42.9g

131g

35.6g

3g

698g

0.1g

[0055] Production method steps:

[0056] Raw material processing: After drying solid raw materials such as medical PVP, sodium bicarbonate, soluble starch, malic acid, and fumaric acid at 80°C for 0.5-3h, grind them finely and sieve them, and take the powders between 200-300μm as Effecti...

Embodiment 1

[0064] Get embodiment 1 to prepare antibacterial effervescent preparation and carry out following efficacy verification and relevant test index:

[0065] 1> Detection of antibacterial rate:

[0066] Sample treatment: Select a blank sanitary napkin sample, tear open the gap from the narrow edge enough for the medicine spoon to pass through, separate the fluff pulp from the upper non-woven fabric with the medicine spoon, take 0.5g of antibacterial effervescent preparation, and use the medicine spoon to separate the fluff pulp from the upper non-woven fabric The effervescent preparation is added between the fluff pulp and the non-woven fabric in the central area of ​​the sanitary napkin, and slightly pressurized. Add 20ml of sterile water to the center area of ​​the above-mentioned sanitary napkin, let it act for 5 minutes, dry it in an oven at 37±2°C for 1 hour, tear off the surface non-woven fabric, and continue drying it in an oven at 37±2°C for 1.5 hours. Cut out the action si...

example 2

[0109] The preparation method of flavor-correcting antibacterial effervescent preparation composition, making 1kg:

[0110] Accurately weigh medical PVP, food-grade ethanol, sodium bicarbonate, triclosan, soluble starch, malic acid, and fumaric acid. The formula is shown in Table 12:

[0111] Table 12: Flavor-modified antibacterial effervescent formulations

[0112] malic acid fumaric acid sodium bicarbonate Medical PVP Triclosan soluble starch β-cycline 8.94％ 4.29％ 13.1％ 3.56％ 0.3％ 48.75％ 30％ 89.4g 42.9g 131g 35.6g 3g 487.5g 300g

[0113] Production method steps:

[0114] Raw material processing: After drying solid raw materials such as medical PVP, sodium bicarbonate, soluble starch, malic acid, fumaric acid, and β-cycloquinone at 80°C for 0.5-3 hours, grind them and sieve them to obtain 200-300 μm The powders in between are used as effective raw materials.

[0115] 1. The first component:

[0116] Dissolve 35.6g of PVP in 25g...

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Abstract

The invention relates to an effervescence preparation composition used for a sanitary towel and a preparation method and application thereof. The effervescence preparation composition is made from thefollowing raw material by weight proportion: 7 to 10 percent of malic acid, 3 to 5 percent of boletic acid, 10 to 15 percent of sodium bicarbonate, 1 to 4 percent of medical PVP, 35 to 70 percent oftragantine, 0.05 to 0.3 percent of triclosan and 0 to 30 percent of additive agent which contains at least one kind of sodium dodecyl sulfate, beta-cyclodextrin, glycerin, lanoline, propolis and jasmine essence. The effervescence preparation composition adopts the raw materials in the food grade and is safe without toxicity. The preparation adopts the powder technology. After the preparation encounters water, acid and alkali in the preparation are subjected to neutralization reaction to produce gas. The repulsive interaction of the gas accelerates the dissolution rate of the preparation in thewater, makes efficacy ingredients rapidly dissolve, solves the problem of unobvious drug effect of a solid preparation, improves the utility ratio of the content of effective ingredients of a liquidpreparation and can be used for preparing sanitary towels, sanitary protecting mats or panty-shape diapers.

Description

technical field [0001] The invention relates to an effervescent preparation, in particular to an effervescent preparation composition for sanitary napkins, a preparation method and application. Background technique [0002] At present, effervescent preparations are widely used in the pharmaceutical and food industries in the market, among which tablets and granules are mostly. When the effervescent preparation meets water, it generates gas through acid-base neutralization reaction, accelerates the disintegration of the preparation in water, makes the preparation quickly dissolve in water, forms a liquid preparation, is convenient to use, and overcomes the difficulty of swallowing tablets and capsules. [0003] With the continuous improvement of people's living standards, it is necessary to provide more medical and food health care products. For example, most of the finishing agents for sanitary napkins (pads) on the market are liquid preparations, and most of the raw materia...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/44A61F13/15A61L15/26A61L15/20A61L15/18
Inventor 韩海星王滨张巍李伟李冬辛亮亮
Owner 韩海星
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