Keke tablets and preparation method thereof

Abstract

The invention discloses a Keke tablet. The composition thereof comprises dry extract powder from medicinal materials, sucrose powder, medical talc powder, medical silicon dioxide, medical magnesium stearate and 20-95% of medical alcohol. The preparation method thereof is as follows: firstly, the sucrose powder and the 20-95% of medical alcohol are mixed evenly, and then mixed with the dry extract powder from the medicinal materials evenly to prepare tiny particles which take moist sucrose particles as crystal nucleus and are externally wrapped with the dry extract powder from the medicinal materials, subsequently the particles are evenly mixed with the raw materials like medical talc powder, medical silicon dioxide and magnesium stearate in accordance with a certain weight proportion, and then tabletting is carried out to prepare the Keke tablet. The invention effectively improves the hardness and stability of the Keke tablet; greatly reduces the occurrence of incapability of coating film, poor stability, failed test, and the like, caused by insufficient hardness of uncoated tablets, split tablets, loose tablets and coarse surface in the processes of production, transportation and storage of preparations; guarantees the operability of the Keke tablet of the invention during production as well as performance stability of the products in the validity period; furthermore, the preparation process is simple and easy to operate, and the production cost is low.

Description

【Technical field】 [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a Keke tablet for treating cough and shortness of breath and a preparation method thereof. 【Background technique】 [0002] Keke Tablets is a Chinese patent medicine with the functions of relieving cough, relieving asthma and eliminating phlegm. It is used for the treatment of cough and shortness of breath. Composition of traditional Chinese medicine. The existing Keke tablet preparation method is to take ephedra and poppy shells and crush them into fine powder, sieve, and keep 45.8% fine powder for later use; add acidic aqueous solution (use 10% hydrochloric acid solution to adjust the pH to about 5) and decoct the remaining coarse powder Second time, add water 10 times for the first time, add water 8 times for the second time, 2 hours each time, filter, adjust the pH value of the filtrate to 7 with 10% sodium hydroxide solution, an...

AI Technical Summary

Problems solved by technology

The drug has been widely used in the treatment of cough and shortness of breath due to its good curative effect and convenient administration. The proportion in each Keke Tablet is 61.1%, and the obtained plain tablet (the plain tablet is the tablet before the film coating) is very prone to poor hardness, easy to split, loose Problems such as unresolved, unable to be film-coated or surface rough after film-coating, so that the existing Keke tablets often have problems such as splits, poor stability, and unqualified testing within the validity period, which are difficult to be accepted by manufacturers and consumers