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Use of sea collagen peptides in preparing medicine or food for protecting kidney function, delaying chronic renal failure

A marine collagen peptide, marine technology, applied in the preparation of drugs to protect kidney function, marine bioactive oligopeptides and their new uses, health food or food, marine collagen peptides

Inactive Publication Date: 2009-03-25
珍奥集团股份有限公司 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] At present, there are few studies on the delaying effect of marine bioactive peptides. If the development of health food can protect kidney function, prevent CKD, delay the progress of renal failure, and slow down the speed of patients entering end-stage renal failure, it is economical and practical. It will bring great prospects to my country's health care industry

Method used

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  • Use of sea collagen peptides in preparing medicine or food for protecting kidney function, delaying chronic renal failure
  • Use of sea collagen peptides in preparing medicine or food for protecting kidney function, delaying chronic renal failure
  • Use of sea collagen peptides in preparing medicine or food for protecting kidney function, delaying chronic renal failure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0016] Example: Marine Collagen Peptide Delays the Effect of Adenine-induced Chronic Renal Injury in Rats

[0017] Thirty-two healthy clean-grade male SD rats, weighing 233.31±6.26g, were provided by the Experimental Animal Center of Peking University Health Science Center. They were raised in a clean-grade animal room with a temperature of 25°C and a humidity of 60%RH. After the rats were adaptively fed for 3 days, the animals were randomly divided into four groups A, B, C and D according to body weight, with 8 rats in each group. The levels of serum inosine and urea nitrogen in the four groups were adjusted to ensure that there was no significant difference in the initial serum inosine and urea nitrogen levels of animals among the groups. Group A is the control group; Group B is the chronic renal injury model group; Group C is the MCPs 1.125g / kg / d intervention group; D group is the MCPs 2.25g / kg / d intervention group, and the doses of MCPs in the two intervention groups were ...

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Abstract

The invention relates to a marine collagen peptide and the application thereof in the preparation of medicine, health food or food used for the protection of renal function and slowing the progress of chronic renal failure. Marine collagen peptide is a group of low-molecular weight oligopeptide mixture generated through the hydrolysis of fish skins of marine fish (salmon, chinook salmon, tilapia and the like). The molecular weight of 70%-80% of oligopeptide is distributed between 200-1000Da. The marine collagen peptide has the advantages of easy absorption, fast absorption, low viscosity, good water-solubility. The experiments prove that the marine collagen peptide can have the efficacy of slowing the adenine-induced chronic renal function impairment of rats.

Description

technical field [0001] The invention relates to a marine bioactive oligopeptide and its new application, in particular to the application of the marine collagen peptide extracted from marine fish in the preparation of kidney function-protecting medicine, health food or food. It belongs to the field of medicine and food health care. Background technique [0002] Chronic kidney disease (chronic kidney disease, CKD) has become the number one invisible killer threatening human health due to its hidden onset, posing great harm to the quality of human life and social development. The significant increase in the incidence of CKD may be related to the following factors: (1) The incidence of hypertension and diabetes is increasing year by year, and hypertension and diabetes are important causes of CKD; (2) With the improvement of people's living standards The incidence of acute nephritis has decreased significantly, but the incidence of chronic nephritis has not decreased, and even ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/60A61K38/39A61P13/12A23L1/305A23L33/18
Inventor 李勇赵海峰王军波
Owner 珍奥集团股份有限公司
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