Rat breathing mask

Abstract

The invention provides a rat respiratory mask which is applicable to basis research, application research, evaluation of medicine function mechanism and treatment effect, and the like, by using acute and chronic myocardial ischemia model of rat as a platform. The rat respiratory mask of the invention consists of a rat jaw fixer (figure 1), a mask body (figure 2), a tooth protection gap (figure 3), a mask fixer (figure 4), a mask air inlet pipe (figure 5), a mask exhaust pipe (figure 6) and an exhaust pipe resistance adjuster (figure 7); wherein, the jaw fixer is made of metal material; the front end of the jaw fixer is an open ellipse and used for fixing the head of the rat; the center of the front part of the mask is provided with a gap which is called the tooth protection gap which has the effect of protecting the fore-teeth of the rat against damage; the mask fixer is arranged at the rear part of the mask; two sides of the mask are respectively provided with an elastic ring which has an effect of fixing the mask; the bottom of the mask is respectively provided with the mask air inlet pipe and the exhaust pipe; the air inlet pipe is connected with the air outlet of a respiratorymachine; the end of the mask exhaust pipe is provided with a resistance adjuster which is used for adjusting the pressure in the aspiratory mask.

Description

technical field [0001] The invention is suitable for basic research, application research, research on drug action mechanism and evaluation of therapeutic effect in the field of medical cardiovascular medicine based on rat acute and chronic myocardial ischemia models. Background technique [0002] Myocardial ischemia, myocardial infarction and heart failure are one of the major killers of human diseases. They have already attracted great attention from the medical circles at home and abroad, and their research has been continuously deepened and gratifying achievements have been made. However, a large number of mechanism studies and drug studies are based on acute myocardial ischemia, but there are relatively few studies on chronic myocardial ischemia. One of the most important reasons is that the success rate of chronic myocardial ischemia model preparation in rats is low and the mortality rate is low. These problems have become bottlenecks in the research of chronic myocard...

AI Technical Summary

Problems solved by technology

The experiment further found that the stenosis or blockage of the nasopharyngeal tube is the direct cause of dyspnea or suffocation. Because the airflow of the upper respiratory tract is blocked after the tracheotomy and intubation, coupled with the slender characteristics of the nasopharyngeal tube, secretions are easy to cause blockage of this site, and it was also found that rats are not good at mouth breathing under anesthesia.

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