A zinc-manganese-magnesium alloy interface screw for reconstruction and fixation of anterior cruciate ligament

An anterior cruciate ligament and interface screw technology, used in surgical fixation nails, surgery, medical science, etc., can solve the problems of affecting fixation stability, high brittleness, and low mechanical strength of as-cast pure Zn, and achieve inhibition of growth and adhesion. , reducing the effect of osteolysis

Active Publication Date: 2022-05-13
PEKING UNIV THIRD HOSPITAL
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  • Abstract
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Problems solved by technology

However, as-cast pure Zn has low mechanical strength and high brittleness, which affects the stability of initial immobilization and has certain cytotoxicity.

Method used

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  • A zinc-manganese-magnesium alloy interface screw for reconstruction and fixation of anterior cruciate ligament
  • A zinc-manganese-magnesium alloy interface screw for reconstruction and fixation of anterior cruciate ligament
  • A zinc-manganese-magnesium alloy interface screw for reconstruction and fixation of anterior cruciate ligament

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Embodiment Construction

[0034] The technical solution of the present invention is described in detail below through the examples, and the following examples are only exemplary and can only be used to explain and illustrate the technical solution of the present invention, rather than being interpreted as a limitation to the technical solution of the present invention.

[0035] like Figure 1 to Figure 5 As shown, in order to improve the degree of bone tissue immersion and bone healing speed, the high-strength zinc-manganese-magnesium alloy interface screw applied to the reconstruction and fixation of the anterior cruciate ligament claimed by the present invention is a hollow interface screw with side holes. According to CT Based on the results of three-dimensional reconstruction, combined with different heights, weights, ages and degrees of osteoporosis, a matching hollow interface screw with side holes was selected; the interface screw was made of high-strength low-alloyed Zn08Mn01Mg or Zn08Mn04Mg, an...

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Abstract

The invention provides a zinc-manganese-magnesium alloy interface screw for reconstruction and fixation of anterior cruciate ligament. Zinc-manganese-magnesium alloy interface screw is a hollow interface screw with side holes, made of high-strength low-alloyed Zn08Mn01Mg or Zn08Mn04Mg; an annular groove is opened on the inner wall of the side hole of the interface screw, and the annular groove is filled with Determine the drug; the length and outer diameter of the interface screw are determined according to the results of preoperative CT three-dimensional reconstruction. Zn in the alloy degradation product that the present invention adopts 2+ With a low concentration, the proliferation efficiency of cells was hardly affected, and there was no obvious immune rejection and inflammatory cell infiltration in the surrounding tissue of implanted experimental screws. In addition, the slow degradation rate of Zn-Mn-Mg alloy in vivo makes it more tightly combined with the surrounding bone tissue, thereby improving the fixation strength.

Description

Technical field: [0001] The invention relates to a degradable zinc-manganese-magnesium alloy interface screw used for reconstruction and fixation of anterior cruciate ligament with high biocompatibility, antibacterial function and function of promoting tendon-bone healing. Background technique: [0002] Interface screws are currently the most commonly used direct fixation device in ACL reconstruction. Interface screws and suture anchors are routinely used to connect soft tissues (such as ligaments and tendons) to bone during surgery. Interface screw fixation provides a force fit between bone, graft / tendon, and screw and is often used to secure replacement ligaments in tunnels for ACL and PCL reconstructions. Implants vary in their composition and can be classified as metallic, polymeric, and composite materials, as well as absorbable fixatives, with varying effectiveness. [0003] Most interface screws currently approved for clinical use are made of metal, the most commonly...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/56
CPCA61L31/022A61L31/047A61L31/148A61L31/14A61L31/16A61B17/0642A61L2300/404A61L2300/412A61L2300/406A61L2300/252A61B2017/0648C08L89/00
Inventor 王健全张辛黄洪杰孙疆张智昱周毕云王成鞠晓东代岭辉王鲁宁石章智
Owner PEKING UNIV THIRD HOSPITAL
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