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External medicine composition for treating gout

A technology of externally used drugs and compositions, applied in the direction of drug combinations, active ingredients of hydroxyl compounds, medical preparations containing active ingredients, etc., can solve the problems of difficult control of production quality, complex composition, toxic and side effects, etc., and achieve the treatment of gouty redness Painful, evenly distributed, less irritating effect

Inactive Publication Date: 2009-01-07
YUNNAN INST OF MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the remaining traditional Chinese medicine compositions for the treatment of gout are all oral preparations, the composition is relatively complicated, and the production quality is difficult to control
The cost is high, and there are more or less certain toxic and side effects on the human body

Method used

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  • External medicine composition for treating gout
  • External medicine composition for treating gout
  • External medicine composition for treating gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Weigh 42 parts of Lijiang Arrowhead mushroom, 42 parts of Aescinus stems and leaves, 42 parts of golden leaves, 42 parts of hemp grass, 42 parts of Phellodendron cork, 42 ​​parts of Baiji, 42 parts of rhubarb, 6 parts of menthol and eight herbs. Grind Qiwei except menthol into coarse powder, mix well, impregnate twice with 65% ethanol for 30 days each time, combine the impregnating liquid, refrigerate for 48 hours, filter, collect the filtrate, add menthol and mix well, and The liquid medicine is poured into a clean container, and the propane-butane gas is pressed in by a press machine to obtain the aerosol for treating gout.

Embodiment 2

[0063] Weigh 35 parts of Lijiang Arrowhead mushroom, 35 parts of Aescinus stems and leaves, 35 parts of golden leaves, 35 parts of hemp grass, 35 parts of Cortex Phellodendri, 35 parts of Baiji, 35 parts of rhubarb, and 5 parts of menthol. Grind Qiwei except menthol into coarse powder, mix well, impregnate twice with 65% ethanol for 30 days each time, combine the impregnation liquid, filter, and collect the filtrate; recover ethanol from the filtrate, concentrate to a relative density of 1.20-1.25 (50°C) thick paste; weigh an appropriate amount of glycerin, add it to the above thick paste, make it fully mix and dissolve, and let it cool; dissolve menthol with 95% ethanol, mix with the obtained thick paste, and set aside; The water-based polymer material is used as the matrix, and appropriate polymer materials (carbomer, cellulose derivatives, sodium alginate, etc.) are added according to conventional techniques; solvents (glycerin, purified water); neutralizers (triethanolamine...

Embodiment 3

[0065] Weigh 16 parts of Lijiang Arrowhead mushroom, 16 parts of Aescinus stems and leaves, 16 parts of golden leaves, 16 parts of hemp grass, 16 parts of Cortex Phellodendri, 16 parts of Baiji, 16 parts of rhubarb and 2 parts of menthol. Grind the remaining Qiwei medicinal materials except menthol into coarse powder, mix well, percolate with 65% ethanol, soak for 48 hours, percolate, collect the leachate, refrigerate for 48 hours, filter; add menthol, mix well, pack separately , to obtain a liniment for treating gout.

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Abstract

The invention relates to a medicament composition for external administration, which cures arthrolithiasis, in particular to a medicament composition for external administration, which cures arthrolithiasis and is prepared from the Chinese medicinal plant herb. The medicament composition for curing arthrolithiasis is a preparation for external administration prepared from the following raw materials by the weight ratio: 16 to 68 parts of Iphigenia indica A.Gray, 16 to 68 parts of scandent schefflera root, 16 to 68 parts of Yunnan craibiodendron leaf, 16 to 68 parts of Tali falsehellebore herb, 16 to 68 parts of amoorcorn tree bark, 16 to 68 parts of bletillae rhizome, 16 to 68 parts of rhubarb and 2 to 10 parts of menthol. The medicament composition for external administration is used for curing the arthrolithiasis disease.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating gout, in particular to an external pharmaceutical preparation composition for treating gout made from plant and Chinese herbal medicines. Background technique [0002] Gout is a disease caused by purine metabolism disorders and continuous elevation of serum uric acid due to hereditary or acquired etiology. It is caused by the accumulation of uric acid caused by excessive uric acid production or insufficient uric acid excretion. Uric acid crystals accumulate in cartilage, soft tissue, kidneys and joints. Deposits in joints can cause severe pain. The clinical manifestations are hyperuricemia (hyperuriccmia) and characteristic acute arthritis, tophi formation, tophi chronic arthritis, and urate nephropathy, uric acid urinary stones, etc. may occur, and joint disability may occur in severe cases , Renal insufficiency. Gout is often accompanied by central obesity hyperlipidemia, diabetes,...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P19/06A61K31/045
Inventor 朱兆云王京昆尚建华刘波徐榕雪谢建平钟关萍杨坤芬孙敏崔涛段丽萍毛勇
Owner YUNNAN INST OF MATERIA MEDICA
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