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Chinese medicinal composition for treating endometriosis symptoms and preparation thereof

A technology of endometrium and composition, which is applied in the field of pharmaceutical composition and preparation of the composition, traditional Chinese medicine composition for treating endometriosis and its preparation, and can solve the problem of unstable curative effect, easy relapse, and many sequelae And other issues

Inactive Publication Date: 2008-09-17
BEIJING HERUN INNOVATION PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This treatment method often has side effects of varying degrees, such as loss of appetite, nausea, abnormal liver function, etc. It is not suitable for people with high blood pressure, heart disease or renal insufficiency, and it is contraindicated for women with liver diseases.
There are also some patients whose curative effect is not stable enough after long-term use, and are prone to relapse after drug withdrawal.
[0006] 2. Surgical treatment Surgical treatment is the main method of endometriosis, and it is easy to relapse after operation and has many sequelae

Method used

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  • Chinese medicinal composition for treating endometriosis symptoms and preparation thereof
  • Chinese medicinal composition for treating endometriosis symptoms and preparation thereof
  • Chinese medicinal composition for treating endometriosis symptoms and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0154] Prescription: Salvia miltiorrhiza 600g, curcuma 300g, coix seed 600g, blood jerky 30g

[0155] Preparation method: take the above four flavors, take 5 times the amount of ethanol and reflux to extract for 1 hour, filter, recover the ethanol from the filtrate, filter, dry the filter residue at low temperature, grind it into fine powder, and set aside; add 6 times the amount of 60% ethanol to the dregs and reflux Extract 2 times, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, and continue to concentrate to a clear paste with a relative density of 1.15 (50-60°C), and set aside; take Curcuma, crush it into a coarse 5-mesh sieve Granules, add 12 times the amount of water, steam distillation for 6 hours to extract the volatile oil, collect the volatile oil, add 5 times his cyclodextrin and 12 times the amount of water, grind for 60 minutes, make inclusion compound, dry (40~50℃) , crushed into fine powder, and set aside; the water ...

Embodiment 2

[0157] Prescription: Salvia miltiorrhiza 480g, curcuma 300g, coix seed 480g, blood jerky 60g

[0158]Preparation method: take the above four flavors, take 6 times the amount of 90% ethanol and soak for 2 hours, filter, recover the ethanol from the filtrate, filter, dry the filter residue at low temperature, grind it into fine powder, and set aside; add 5 times the amount of 50% ethanol to the dregs Reflux extraction twice, each time for 1 hour, filter, combine the filtrates, recover ethanol under reduced pressure, and continue to concentrate to a clear paste with a relative density of 1.15-1.20 (50-60°C), and set aside; take curcuma, crush it into 5-mesh Sieve the coarse particles, add 12 times the amount of water, steam distill for 6 hours to extract the volatile oil, collect the volatile oil, add 6 times his cyclodextrin and 14 times the amount of water, grind for 60 minutes, make the clathrate, dry (40~ 50°C), crushed into fine powder, and set aside; filtered the water, con...

Embodiment 3

[0160] Prescription: motherwort 600g, curcuma 300g, coix seed 600g, blood jerky 30g

[0161] Preparation method: Take motherwort from the above four flavors, add 8 times the amount of water to decoct 3 times, each time for 1 hour, filter, combine the filtrate, concentrate to a relative density of 1.05-1.10 (60°C), add ethanol to make the alcohol content 80%, let it stand for 24 hours, filter, the filtrate decompresses to recover ethanol, and continues to concentrate to a clear paste with a relative density of 1.10~1.15 (50~60°C), and set aside; take Curcuma, crush it into a coarse 5-mesh sieve Granules, add 12 times the amount; steam distillation for 8 hours to extract volatile oil, volatile oil for later use, water filtration, concentrated into a clear paste with a relative density of 1.15-1.20 (50-60°C), add 1 times the amount of ethanol to precipitate for 24 hours, filter After filtration, the filtrate is recovered with ethanol and concentrated into a clear paste of 1.10-1....

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Abstract

The invention discloses a Chinese medicine composition for treating endometriosis uterine, belonging to the technical field of Chinese medicine, which is characterized in that a plurality of medicinal herbs, such as radix salviae miltiorrhizae, motherwort, Rhizoma Zedoariae, semen coicis, dragon's blood are used as raw materials, and undergo the processes of alcohol extraction and water extraction according to relevant compatibility requirements, so as to produce the intended medicine preparation, and the Chinese medicine composition is optimally manufactured into capsules. The Chinese medicine composition has an advantage of remarkable curative effect for endometriosis uterine.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method of the composition, in particular to a traditional Chinese medicine composition for treating endometriosis and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] Endometriosis refers to the endometrium that should have covered the surface of the uterine body cavity. Due to some factors, it grows in other parts of the body, which can become endometriosis. Histologically, this ectopic endometrium is not only surrounded by endometrial glands, but also surrounded by endometrial stroma; functionally, it changes significantly with the level of estrogen, that is, changes with the menstrual cycle, but only some Affected by progesterone, it can produce a small amount of "menstruation" and cause various clinical phenomena. If the patient is pregnant, the ectopic endometrium may have decidua-like changes. [0003] Many ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/906A61K9/48A61P15/00
Inventor 李钦青王广录
Owner BEIJING HERUN INNOVATION PHARMA TECH DEV
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