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Medicament for treating chronic kidney disease proteinuria and preparation thereof

A technology for chronic kidney disease and proteinuria, which is applied in the preparation of the drug and in the field of traditional Chinese medicine preparations for the treatment of kidney disease, to achieve good curative effect, improve curative effect, and improve hemorheology indicators

Inactive Publication Date: 2008-08-20
FIRST HOSPITAL OF SHANXI MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Some recognized drugs currently used to control proteinuria, such as ACEIs, ARBs, glucocorticoids, and immunosuppressants, have certain limitations in clinical use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Take 100Kg of Astragalus, 75Kg of Alisma, 50Kg of Schisandra, 75Kg of Gorgon, and 150Kg of lotus roots into the extraction tank, add 500Kg of water, decoct for 2h, filter out the decoction, add the same amount of water, decoct twice, each time 2h. The three decoctions are combined, filtered, concentrated into a thick paste with a relative density of 1.20 to 1.24, dried and crushed into a fine powder of 80 mesh, filled into capsules, sterilized, and made into a capsule product.

Embodiment 2

[0044] Take 150Kg of Astragalus, 50Kg of Alisma, 40Kg of Schisandra, 50Kg of Gorgon, and 100Kg of lotus roots into the extraction tank, add 500Kg of water, decoct for 2h, filter out the decoction, add the same amount of water, decoct twice, each time 2h. The three decoctions are combined, filtered, concentrated into a thick paste with a relative density of 1.20 to 1.24, dried and crushed into a fine powder of 80 mesh, filled into capsules, sterilized, and made into a capsule product.

Embodiment 3

[0046] Take 80Kg of Astragalus, 75Kg of Alisma, 60Kg of Schisandra, 75Kg of Gorgon, and 200Kg of lotus root joints into the extraction tank, add 500Kg of water, decoct for 2h, filter out the decoction, add the same amount of water, decoct twice, each time 2h. The three decoctions are combined, filtered, concentrated into a thick paste with a relative density of 1.20 to 1.24, dried and crushed into a fine powder of 80 mesh, filled into capsules, sterilized, and made into a capsule product.

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Abstract

The invention relates to a drug for treating chronic kidney disease proteinuria, which is a capsules prepared as follows: the materials are astragalus, Oriental Waterplantain Rhizome, Chinese Magnolivine Fruit, fried foxnut and node of lotus rhizome, which are added to water to be decocted, and the decoction solution is concentrated and dried. The drug has the advantages of kidney invigorating, diuresis inducing and stranguria treating, blood activating and stasis removing, swelling reducing and pain alleviating, heat-clearing and detoxifying, body fluid regenerating and thirst quenching, darrhea relieving, cough relieving and bleeding stopping, which has the function of body immunity regulation and reinforcing, and is suitable for the patient with chronic kidney disease and chronic renal failure proteinuria; the drug can effectively reduce proteinuria, increase plasma albumin, reduce the pathological changes of kidney and improve hemorheology indexes, which has a certain controlling effect on hematuria and proteinuria. In clinical verification, the drug has the advantages of fast therapeutic effect, good efficacy and small side effect.

Description

Technical field [0001] The invention relates to a medicine, in particular to a traditional Chinese medicine preparation for treating nephropathy. The invention also relates to a preparation method of the medicine. Background technique [0002] Chronic kidney disease is a common clinical disease, but because the early symptoms are not obvious, it is easy to be ignored by people. Approximately 20% of kidney disease patients lack knowledge about the prevention and treatment of kidney disease, and their condition is often in the advanced stage when they first come to the hospital for treatment. In addition, patients with chronic kidney disease are prone to many complications. For example, the incidence of cardiovascular disease is dozens of times higher than that of the normal population, and it can also cause anemia, bone disease, malnutrition, and decreased sexual function. If the prevention and treatment of chronic kidney disease is not paid attention to in the early stage, it wil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61K9/48A61P13/12
Inventor 方敬爱
Owner FIRST HOSPITAL OF SHANXI MEDICAL UNIV
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