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Medicament for treating nausea emesis caused by radiotherapy and chemotherapy

A technology of nausea and vomiting, medicine, applied in the direction of medicine combination, digestive system, medicine formula, etc., can solve the problems of high price, unacceptable normal treatment, affecting disease control, etc., achieve less toxic side effects, promote disease improvement, and lower treatment cost Effect

Inactive Publication Date: 2010-06-02
张旭梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The most common adverse reactions are headache, constipation, abdominal distension, diarrhea, drowsiness, etc. Toxic side effects such as sedation, hallucinations, hallucinations, elevated blood pressure, and changes in electrocardiogram may also occur to varying degrees, and it is ineffective for delayed vomiting
In addition, some of the above-mentioned drugs are expensive, and most patients cannot receive normal treatment due to unaffordable financial conditions, which seriously affects the control of the disease.

Method used

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  • Medicament for treating nausea emesis caused by radiotherapy and chemotherapy
  • Medicament for treating nausea emesis caused by radiotherapy and chemotherapy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Take 8Kg of Clematis clematis and 2Kg of ginger, pick out impurities, screen and wash, dry and crush into fine powder, add to 10L of water and decoct for 60min, add the same amount of water to decoct for 60min with medicinal dregs, combine 2 times of decoction, Filter, concentrate to a concentrated solution containing 2g of crude drug per milliliter, adjust the pH value to 6-7, let it stand for 24 hours, fill it into 10mL / bottle of oral solution, and sterilize it according to conventional preparations.

Embodiment 2

[0044] Take 6Kg of Clematis clematis and 4Kg of ginger, pick out impurities, screen and wash, dry and crush into fine powder, add to 10L of water and decoct for 60 minutes, add the same amount of water to the dregs and decoct for 60 minutes, combine 2 times of decoction, Filtrate, condense into a clear paste with a relative density of 1.14 (50°C), use sucrose fine powder as an auxiliary material, make granules containing 1-2 g of crude drug per 1 g, pack into bags, and sterilize according to conventional preparations.

Embodiment 3

[0046] Take 4Kg of Clematis clematis and 6Kg of ginger, pick out impurities, screen and wash, dry and crush into fine powder, heat and extract with 20L of 60% ethanol solution twice, each time for 2h, combine extracts, recover ethanol, and concentrate to relative density 1.12 (50°C) clear ointment, add auxiliary materials to make capsules, each capsule contains 3-5g of crude drug.

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Abstract

The present invention relates to a medicine for curing nausea and vomit caused by radiotherapy and chemotherapy, including 10 to 90 portions of clematis root and 10 to 90 portions of ginger. The medicine provided by the present invention can effectively cure and prevent vomit caused by radiotherapy and chemotherapy and intractable naupathia and vomit caused by various reasons. Compared with medicines for curing vomit such as ondansetron, the present invention with quick effect, high curing effect and more than 95 percent curing rate has obvious curing effect on various acute and slow vomit, which can increase the appetite of patients, strengthen body resistance and improve disease conditions. In addition, the present invention has small side effect, convenient use and low curing expense.

Description

technical field [0001] The invention relates to a medicine for treating nausea and vomiting caused by radiotherapy and chemotherapy, in particular to a medicine for treating nausea and vomiting caused by radiotherapy and chemotherapy prepared from traditional Chinese medicine. The medicine of the present invention can treat and prevent emesis caused by radiotherapy and chemotherapy and intractable emesis caused by various reasons. Background technique [0002] Radiotherapy and chemotherapy are practical and effective methods for the current treatment or auxiliary surgical treatment of cancer, but these two methods will kill other healthy cells while killing cancer cells in patients. Therefore, the biggest defect of radiotherapy and chemotherapy is that it will bring a series of side effects of different degrees such as nausea, vomiting, loss of appetite, and leukopenia to patients. Some patients suffer from severe dehydration, electrolyte imbalance, stomach cramps, and gastr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K36/716A61P1/08
Inventor 张旭梅张校科张馨
Owner 张旭梅
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