Method for extracting and separating sodium ketopropionate from acetonic acid fermentation liquid by double membrane two-step process

Abstract

A method for extracting and separating the sodium pyruvate from the pyruvate fermentation broth by adopting the double membrane two-step process comprises the following steps: 1. the sodium pyruvate concentrated solution is extracted and separated through the double membrane process; 2. the sodium pyruvate concentrated solution is used for preparing the sodium pyruvate solids: the sodium pyruvate concentrated solution goes through the production steps such as the ethanol precipitation, separation of the precipitates from the mother liquors, drying, grinding, screening, inspection, finished product packaging, etc. so as to obtain the qualified sodium pyruvate solids. The invention has the advantages of short production process, high product purity, high utilization ratio, high automation degree, few contamination caused to the environment, low production cost, etc., and is especially suitable for the industrialized large-scale production of the sodium pyruvate.

Description

technical field [0001] The invention relates to a method for separating and extracting sodium pyruvate from pyruvate fermentation broth, in particular to a method for extracting and separating sodium pyruvate from pyruvate fermentation broth by a double-membrane two-step method. Background technique [0002] Sodium pyruvate is the sodium salt of pyruvic acid. Pyruvate is a keto acid containing three carbons, a colorless liquid with an odor similar to acetic acid, an important intermediate metabolite in the process of sugar metabolism, and a precursor of many useful compounds. Therefore, it is widely used in chemical industry, It has a wide range of applications in industry and scientific research such as pharmaceuticals and agrochemicals. Since the structure of pyruvate contains two linked carbonyl groups, which leads to the instability of its structure, the pyruvate group usually exists in the form of pyruvate. At present, the common preparation me...

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Problems solved by technology

However, there are many difficulties in applying these methods in industrial production.

[0006] After the precursor pyruvic acid of sodium pyruvate is obtained by the above method, the obtained relatively pure pyruvic acid will be neutralized with alkali. Because the acidity of pyruvic acid is similar to acetic acid, it reacts violently with alkali and emits a large amount of However, due to the instability of pyruvate itself due to its structure, a large amount of pyruvate is decomposed in the reaction process, and the yield of the final product sodium pyruvate is greatly reduced. Taking pyruvate as the starting material, the yield is usually only Within 40%, Chinese patents disclose some production methods of sodium pyruvate, which can show that the existing domestic production methods of sodium pyruvate have shortcomings such as long production lines, high energy consumption, low yield, large pollution, and high cost

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