Compound preparation containing orlistat

Abstract

The invention belongs to the field of medical technique and relates to a compound fat-reducing containing orlistat. The invention basically contains orlistat and synergistic agent, wherein the synergistic agent is one or several ingredients chosen from pulullan saccharide, chitin, vitamin A, vitamin D, vitamin E, vitamin K and / or beta-carotene. Any solid preparation for oral administration can be made by charging other active component or finding component on the basic components. The invention is characterized in that quick fat reducing can be achieved by inhibiting the absorption of exogenous fat, meanwhile the adsorption action of pulullan saccharide, chitin and other amylase is brought in to effect, the ipidized loose bowel movement, unctuous stool, anal fistula and other side effects of the patient of adiposis are reduced, and fatsoluble vitamin reduced by absorption is complemented.

Description

technical field [0001] The invention belongs to the technical field of medicine and relates to a compound weight-loss preparation containing orlistat. Background technique [0002] Obesity is a common disease worldwide. When the human body eats more calories than it consumes, the excess calories are stored in the body in the form of fat, resulting in weight gain. It is a chronic metabolic disease, and its incidence is increasing year by year. Obesity is not only unattractive, but also has many hidden dangers. It is often associated with type II diabetes, high blood pressure, dyslipidemia, gout, gallstones, atherosclerosis, coronary heart disease, etc. It has gradually become one of the most important global health problems . In terms of weight loss drugs, there are drugs such as sibutramine and orlistat on the market. Among them, sibutramine is an appetite suppressant, which can achieve weight loss by suppressing appetite and reducing eating. Orlistat is a specific inhibi...

AI Technical Summary

Problems solved by technology

Side effects of long-term use of orlistat: oily feces, anal oil leakage and other adverse reactions affect the work and life of patients, and at the same time, it is easy to reduce the intake of fat-soluble vitamin A, vitamin D, vitamin E, vitamin K and β-carotene

[0005] In addition, Chinese Invention Patent Publication No. CN 1373656A discloses a dispersed solid containing a lipase inhibitor. The preferred lipase inhibitor is orlistat, which can effectively reduce the fatty stool, Occurrence of adverse reactions such as anal oil leakage, but its weight loss effect is slow

Chinese Invention Patent No. CN 1546017A discloses a compound preparation containing orlistat, L-carnitine, and calcium pyruvate, which work together in inhibiting the absorption of exogenous fat and accelerating the consumption of body fat, so as to achieve the effect of rapid weight loss , but it cannot reduce side effects such as fatty stool and anal oil leakage caused by taking the compound preparation

Neither of the above two patents can overcome the reduction in intake of fat-soluble vitamins in the body caused by long-term use of orlistat

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