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A garlic health care capsule for treating cardiac and cerebral vascular diseases and cancer as well as its preparing method

A technology of cardiovascular and cerebrovascular and ikinin, which is applied in the field of garlic sulfur compounds and its preparation, and can solve the problems of preparing ikinin that have not been seen yet

Inactive Publication Date: 2008-04-09
朱永亮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method of preparing Akinin has not yet been seen

Method used

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  • A garlic health care capsule for treating cardiac and cerebral vascular diseases and cancer as well as its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Add 100 ml of water to 100 grams of fresh garlic cloves, stir gently for 10 minutes, remove the sediment after centrifugation, and obtain about 120 ml of Alysol aqueous solution, containing about 1 gram of Alysol.

[0019] 20 grams of α-cyclodextrin (water content 8.4%) was ground into powder in a mortar, mixed with the above-mentioned aqueous solution of Alisol, and the white mixture thus obtained was further stirred for two hours to make the mixture uniform. Then, it was dried at room temperature. Grind into a fine powder to obtain 20 g of intermediate product. Dissolve the intermediate product in 6000 ml of water and stir for -5 hours. This slightly hazy mixture was extracted three times with 1 L of diethyl ether. The organic phases were extracted to remove water, mixed together and concentrated in a rotary dryer to remove ether.

[0020] 2 g of the residue thus obtained contained 40% ekinin by H-NMR analysis.

Embodiment 2

[0022] Mix 10 grams of γ-cyclodextrin (water content 10%) with 10 milliliters of water containing about 1 gram of Allison to make a uniform paste. The paste was dried under vacuum at 5°C. 10 g of the dried product thus obtained was pulverized, washed with ether and dried. The complex thus obtained was dissolved in 3000 ml of water and stirred for 5 hours, then extracted by the method of Example 1.

[0023] The final residue is about 0.8 grams and contains 50% ekinin.

Embodiment 3

[0025] The preparation method is the same as in Example 2, but the difference is that 40% Alison is used and ethanol diluted with 90% ethanol (2:1). Drying is carried out in a vacuum at 30°C. The powdery dry product flows in 100 ml of diethyl ether It was boiled for 4 hours. Then dissolved in 300 ml of water and extracted three times with 100 ml of ether. Each extraction was carried out in a fluid boil.

[0026] The 1 gram residue thus obtained contained 70% erkinin, 34% cis erkinin and 36% trans erkinin.

[0027] 98% pure Ekinin can be obtained by dissolving the above residue in water, extracting it with n-heptane and diethyl ether, and preparing it by HPLC.

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Abstract

The invention relates to a garlic ajoene for curing the cardio-cerebral vascular disease and the cancer, and the preparation method thereof, and belongs to the technical field of the extraction of the herbal medicine. The ajoene of the invention for curing the cardio-cerebral vascular disease is extracted from fresh garlic, and obtained by the chromatography. The ajoene can prevent the thrombus from forming, distend the coronary artery, enhance the immune function, and inhibit the growth of cancer cells. The ajoene can be made into an oral preparation or injection preparation, which is used to treat the cardio-cerebral vascular diseases of arteriosclerosis and cardiac infarction, etc., prevent and cure the cancer and the tumour.

Description

technical field [0001] The invention relates to a garlic sulfur compound extracted from a herbal medicine and a preparation method thereof, in particular to a preparation of garlic ikinin for treating diseases of the cardiovascular and cerebrovascular systems and cancer. Background technique [0002] With the aging of society and the change of living habits such as diet, the hazards of cardiovascular and cerebrovascular diseases are becoming more and more noticeable. Cardiovascular and cerebrovascular diseases, such as angina pectoris, myocardial infarction, cerebral infarction and other diseases and cancers are becoming more and more common. Garlic has been an important condiment for thousands of years, and it is also the most famous and commonly used folk medicine. It is one of the most popular natural plant extracts in the international market. It can reduce blood viscosity, inhibit platelet aggregation, lower serum cholesterol and triglycerides, improve the body's antivi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P9/00A61P9/10A61P35/00A61K125/00
Inventor 朱永亮
Owner 朱永亮
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