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Medical function of fresh rehmannia root juice for treating and preventing allergic diseases

A technology of fresh rehmannia glutinosa, disease, applied in the field of medicine

Inactive Publication Date: 2007-09-26
罗河生
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The health care use of fresh rehmannia root and fresh rehmannia juice in the treatment and prevention of allergic diseases is not documented

Method used

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  • Medical function of fresh rehmannia root juice for treating and preventing allergic diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] [Example 1] Pharmacological test of fresh rehmannia root juice

[0046] Asthma induced by albumin aerosol inhalation

[0047] Get 30 guinea pigs of 200-250 g, half male and half male, and inject 0.2 ml of 4% ovalbumin saline solution into the lateral muscle of the right hind leg, and simultaneously inject 0.2 ml of 4% aluminum hydroxide gel into the abdominal cavity for sensitization. From the second day of sensitization, the animals were randomly divided into 3 groups: control group and 2 groups with pure fresh rehmannia juice. The treatment group was administered intragastrically for 14 days. After the last dose, the animals were placed in an airtight glass bell jar. After being quiet, the air compressor was started and 3.5% ovalbumin was sprayed at a constant pressure of 53kPa (400mmHg). Saline for 30 seconds, observe the latency period of wheezing convulsions in guinea pigs and the number of animals that convulsed within 6 minutes. (Xu Shuyun, Bian Rulian, edited ...

Embodiment 2

[0071] [Example 2] Take 1000 grams of fresh rehmannia glutinosa, wash it with water, put it in a ventilated place to dry wild water, squeeze the fresh rehmannia glutinosa juice directly to obtain crude and fresh rehmannia glutinosa juice, filter out the residue of the crude and fresh rehmannia glutinosa juice, Obtain clarified pure fresh rehmannia juice 750ml. Pure fresh rehmannia juice contains 1.3% catalpol and 0.35% rehmanthin D. Total rehmannia glycosides is 5.5% in terms of catalpol. 750ml of pure fresh rehmannia juice, add 100g of sugar, 2.0g of VC, add appropriate amount of water to make 1000ml, ultrafilter, pack into 10ml / bottle, and pasteurize. Instantly.

Embodiment 3

[0072] [Example 3] Take 1000 grams of fresh rehmannia glutinosa, wash it with water, pre-cook it in boiling water, take out the fresh rehmannia glutinosa and add 1000 ml of water, beat it, filter it, and obtain 1700 ml of fresh rehmannia glutinosa juice for clarified ingredients. Fresh rehmannia root juice contains 0.5% of catalpol, 0.13% of rehmanthin D, and the content of total rehmannia glycosides is 2.3% based on catalpol. Add 1kg of sugar, 34g of benzoic acid, add an appropriate amount of freshly boiled water to make 34L, carry out ultrafiltration, and divide into 100ml / bottles with high-temperature sterilized glass bottles to obtain fresh rehmannia juice health drink, fresh rehmannia juice health drink containing catalpol 0.026%, total rehmannia glucoside is 0.13% calculated as catalpol.

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Abstract

The invention relates to the use of fresh rehmannia root extract in preparing pharmaceutical composition for the treatment and / or prevention of type I allergic reaction related diseases including allergic asthma, anaphylactic rhinitis, allergic ophthalmocace, allergic skin diseases, anaphylactic dermitis, acute and chronic urticaria.

Description

technical field [0001] The invention relates to the field of medicine, and the medicinal application of fresh rehmannia juice for effectively preventing and treating asthma, allergic rhinitis and other allergic diseases. The invention is particularly suitable for treating and preventing allergic asthma, and can also be used for treating and preventing allergic rhinitis and allergic skin diseases. Background technique [0002] Allergic diseases include asthma, allergic rhinitis, allergic eye disease, allergic skin disease, atopic dermatitis, acute and chronic urticaria, etc. [0003] Bronchial asthma is the most common chronic respiratory disease in the world. It is conservatively estimated that at least 100 million people in the world suffer from asthma. In recent years, its prevalence and mortality have been on the rise. Asthma has become a serious public health problem and has received great attention from all over the world. Therefore, there is a need to provide drugs a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/20A61K9/48A61P11/06A61P37/08A61K127/00
Inventor 罗河生
Owner 罗河生
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