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Traditional Chinese Medicine extract against SARS virus

A SARS virus and drug technology, applied in the field of traditional Chinese medicine extracts, can solve the problem of no anti-SARS virus and the like

Inactive Publication Date: 2010-02-24
GUILIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be said that the research on anti-SARS virus drugs is still in its infancy, and there is no clinically effective anti-SARS virus drug.

Method used

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  • Traditional Chinese Medicine extract against SARS virus

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0010] Rhubarb palmatum was used as raw material to separate and extract rhubarb anthraquinone compounds that can effectively resist SARS virus,

[0011] Specific process such as figure 1 shown.

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Abstract

The present invention discloses one kind of rhubarb anthraquinone compound separated and extracted from rhubarb and with powerful SARS virus inhibiting effect. Extracorporeal experiment shows that thecompound has SARS coronavirus 3C-like proteinase inhibiting rate over 85 % when the medicine dosage is 100 microgram / ml. In addition, the present invention has the features of clear medical speciality of rhubarb, rich medicine resource, clear rhubarb anthraquinone compound structure, determined acting mechanism and mature extraction process, and is significant in developing high efficiency and low toxicity SARS virus resisting medicine.

Description

(1) Technical field: [0001] The invention relates to a traditional Chinese medicine extract, in particular to a traditional Chinese medicine extract capable of effectively resisting SARS virus. (two) background technology: [0002] SARS is a brand-new infectious disease that seriously threatens human health. The main pathogen causing the disease is a new type of coronavirus (SARS coronavirus). At present, clinical treatment mainly focuses on symptomatic treatment, among which the rational application of glucocorticoids is the most important. The use of anti-SARS virus drugs includes: ribavirin, interferon and traditional single antiviral Chinese medicines such as: banlangen, fish smell Grass, Erigeron, etc.; traditional Chinese medicine compound prescriptions such as Qingkailing, Compound Kushen, Jiedu Pills, Jinlian Qingre Granules, etc., but these drugs have limited curative effects, and most of them lack modern scientific experimental basis. Therefore, at present, both a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07C50/16C07C46/10A61P31/14
Inventor 罗伟生徐庆苏小建李胜联刘卫兵梁荣感唐祖年李丽亚韦京辰
Owner GUILIN MEDICAL UNIVERSITY
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