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Ginseng sini injection four treating cold limbs and preparing method

A technology of injections and ginseng, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, powder delivery, etc., can solve problems such as retention, and achieve fast drug effects, increased serum complement content, and good anti-arrhythmic effects

Inactive Publication Date: 2009-12-30
四川三民药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Sini Decoction plus Ginseng Prescription has been recognized by generations of physicians as a classic prescription for restoring yang and rescuing the adversity, nourishing the heart and rejuvenating the pulse, nourishing qi and solidifying, warming the middle and dispelling the cold, there is still no preparation on the market, and it only stays in the prescription of original medicine agent

Method used

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  • Ginseng sini injection four treating cold limbs and preparing method
  • Ginseng sini injection four treating cold limbs and preparing method
  • Ginseng sini injection four treating cold limbs and preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment A

[0053] Embodiment A small capacity ginseng Sini injection

[0054] Extract from Sini Decoction (3-9g of Baifu Tablet or Heishun Tablet, 2-6g of Dried Ginger, 3-9g of Zhigancao or Licorice Root), 1.5-4.5g of Ginseng Extract from Red Ginseng (containing 1.8-5.4 ginsenosides) mg, ginseng polysaccharide 37.5~112.5mg), water for injection is added to 5~20ml.

[0055] Example 1 is composed of Sini Decoction (Baifu Tablet 3g, Dried Ginger 2g, Radix Glycyrrhizae 3g) extract, Red Ginseng 1.5g extract (ginsenoside 1.8g, ginseng polysaccharide 37.5mg), and water for injection 5ml.

[0056] Example 2 consists of Sini decoction (6g of Baifu tablets, 4g of dried ginger, 6g of Zhigancao) extract, 1.5g of ginseng extract (3.6mg of ginsenoside, 75mg of ginseng polysaccharide), and 5ml of water for injection.

[0057] Example 3 is composed of Sini Decoction (9g of Baifu Tablets, 6g of Dried Ginger, and 9g of Radix Glycyrrhizae), 4.5g of Ginseng Extract (5.4mg of Ginsenosides, 112.5mg of Ginsen...

Embodiment B

[0064] Example B large-capacity ginseng four reverse sodium chloride injection

[0065] Extract from Sini Decoction (3-9g of Baifu Tablet or Heishun Tablet, 2-6g of Dried Ginger, 3-9g of Zhigancao or Licorice Root), 1.5-4.5g of Red Ginseng or Ginseng Extract (containing 1.8-5.4 ginsenosides) mg, ginseng polysaccharide 37.5~112.5mg), the total amount of the composition is 0.9% sodium chloride, and water for injection is added to 50~200ml to form.

[0066] Example 1: Extract from Sini Decoction (3g of Baifu tablets, 2g of dried ginger, 3g of Zhigancao), 1.5g of red ginseng extract (containing 1.8mg of ginsenoside, 37.5mg of ginseng polysaccharide), 0.45g of sodium chloride, and water for injection Add to 50ml composition.

[0067] Example 2 is composed of Sini Decoction (6g of Baifu Tablets, 4g of dried ginger, 6g of Radix Glycyrrhizae) extract, 3g of red ginseng extract (containing 3.6mg of ginsenoside, 75mg of ginseng polysaccharide), 0.9g of sodium chloride, and water for in...

Embodiment C

[0074] Example C Large-capacity Ginseng Sini Glucose Injection

[0075] Sini Decoction (Baifu Tablet or Heishun Tablet 3-9g, Dried Ginger 2-6g, Radix Glycyrrhiza or Licorice 3-9g) extract, Red Ginseng or Ginseng 1.5-4.5g extract (containing ginsenoside 1.8-5.4 mg, ginseng polysaccharide 37.5~112.5mg) the total amount of the composition is 5% glucose, and water for injection is added to 50~200ml to form.

[0076] Example 1: Extract from Sini Decoction (Baifu Tablet 3g, Dried Ginger 2g, Radix Glycyrrhizae 3g), Red Ginseng 1.5g extract (containing ginsenoside 1.8mg, ginseng polysaccharide 37.5mg), glucose 2.5g, water for injection 50ml composition.

[0077] Example 2 is composed of Sini Decoction (6g of Baifu Tablets, 4g of dried ginger, 6g of Zhigancao), 3g of red ginseng extract (including 3.6mg of ginsenosides and 75mg of ginseng polysaccharide), 5g of glucose, and water for injection to 100ml.

[0078] Example 3: Extract from Sini Decoction (9g of Baifu Tablets, 6g of Dried...

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Abstract

The ginseng Sini injection for treating Jue syndrome and chest Bi-syndrome consists of giant typhonium tuber slice or Heishun slice, ginger, red sage or ginseng, fried licrorice, medicine supplementary material and water for injection. It may be prepared into injection, transfusion liquid and freeze dried powder for injection. Its preparation process includes preparing Sini decoction with Heishun slice, ginger and fried licrorice via decoction, filtering and alcohol deposition and concentration; treating the Sini decoction dregs via sulfuric acid deposition, drying, acetone extraction and filtering to obtain glycyrrhizic acid and glycyrrhetic acid; processing red sage or ginseng via alcohol reflux, ethyl ether extraction and other step to obtain ginsenoside; treating the red sage or ginseng dregs to obtain ginseng polysaccharide; and other steps. The present invention is used in treating shock, angina pectoris, myocardial infarction and heart failure, and has high bioavailability and other advantages.

Description

technical field [0001] The present invention relates to a method of recovering yang and resuscitating adverse events, nourishing the heart and recovering the veins, nourishing qi and solidifying the detoxification, warming the middle and dispelling the cold (evil), which is used for the treatment of syndromes of deficiency of yin and excess of cold, depletion of yin and degeneration of yang, excess of yin and exuberance of yang. Cardiogenic, hypovolemic, traumatic, toxic and other types of shock) and chest pain syndrome (angina pectoris of coronary heart disease), myocardial infarction, heart failure and other acute and severe new drugs - Ginseng Sini Injection. Another object of the present invention is to extract and purify the active ingredients of Sini Decoction (Baifu Pian or Heishun Pian, dried ginger, roasted licorice or licorice) and red ginseng or ginseng to make a small volume injection suitable for intravenous administration , large-volume injection and freeze-dried...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K36/714A61K36/484A61K36/258A61K9/19A61P9/02A61P9/04A61P9/10A61K9/08
Inventor 罗明生高天惠
Owner 四川三民药业有限公司
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