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Preparing method and application of medicine for treating ischemic encephalopathy and cerebral arteriosclerosis

A technology for cerebral arteriosclerosis and ischemic encephalopathy, which is applied in the field of preparation and application of drugs for treating ischemic encephalopathy and cerebral arteriosclerosis, and can solve the problems of slow onset of action and slow absorption of ginkgo tablets, etc. question

Inactive Publication Date: 2009-09-02
TIANNING PHARMA OF SHAANXI PHARMA HLDG GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On June 16, 2004, the State Intellectual Property Office published a patent application for "Ginkgo Dripping Pills for the Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases". The application number is 02135936, and the publication number is 1504208. The problem of slow absorption rate and slow onset after medication, it is composed of the following raw material components in parts by weight: 1-60 parts of Ginkgo biloba extract, 0-60 parts of Salvia miltiorrhiza extract, 20-80 parts of matrix

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1: get 15 groups of medicine compositions, the weight composition of medicine is respectively: Radix Puerariae 1400, 1450, 1500, 1550, 1580, 1600, 1680, 1650, 1700, 1750, 1800, 1850, 1900, 1950 and 2000 grams, Ginkgo biloba 1400, 1450, 1500, 1550, 1600, 1650, 1680, 1700, 1750, 1780, 1800, 1850, 1900, 1950 and 2000 grams, borneol 5.5, 5.8, 6.0, 6.3, 6.5, 6.8, 6.9, 7.0, 7.27.3, 7.5, 7.8, 8.0, 8.3 and 8.5 grams.

[0019] The preferred ratio of the weight of Pueraria lobata root and Ginkgo leaf is: Pueraria lobata: Ginkgo leaf=1:1.

[0020] The preparation method of the medicine for ischemic encephalopathy and cerebral arteriosclerosis disease, according to the above-mentioned components, three herbal medicines are selected, wherein the two medicines of kudzu root and ginkgo biloba are respectively selected, rinsed, dried, mixed together and pulverized into a coarse powder, add 70% ethanol respectively according to the above fifteen components, reflux extraction...

Embodiment 2

[0022] Embodiment 2: As the application of the medicine for the treatment of ischemic encephalopathy and cerebral arteriosclerosis disease, granulate with the above-mentioned dry cream powder or dry powder plus the borneol solution dissolved in absolute ethanol, and prepare with existing mature technology into solid form, the solid form is tablet, granule, powder, capsule, powder injection; wherein the active part content of each preparation unit of the solid form is 0.1 g to 1.0 g.

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Abstract

The invention relates to a preparation method and application of a medicine for cerebral embolism, cerebral vasospasm and other ischemic encephalopathy and cerebral arteriosclerosis. The original name is Jengke Capsule. Currently on the market, there are drugs for the treatment of cerebral embolism, cerebral vasospasm and other ischemic encephalopathy and cerebral arteriosclerosis diseases, symptomatic treatment. The purpose of the present invention is to develop a method for promoting blood circulation and removing stasis, dredging channels and relieving collaterals, relieving spasm and relieving pain, and enhancing brain and coronary blood flow in the treatment of cerebral embolism, cerebral vasospasm and other ischemic encephalopathy and cerebral arteriosclerosis. Flow, preparation method and application of medicine for treating ischemic encephalopathy and cerebral arteriosclerosis. The technical scheme of the present invention: medicine kudzu root gram, ginkgo leaf, borneol, preparation method, after selection, washing, drying, mixing, crushing, adding ethanol, extracting liquid, concentrating, standing, suction filtration, spray drying, granulation, etc. The process obtains the drug. Advantages have the functions of promoting blood circulation and removing blood stasis, dredging channels and relaxing collaterals, and are clinically used for cerebral thrombosis and thrombotic cerebral infarction.

Description

1. Technical field: [0001] The invention relates to a preparation method and application (use) of a medicine for cerebral embolism, cerebral vasospasm and other ischemic encephalopathy and cerebral arteriosclerosis. Formerly known as: JG Capsule. 2. Background technology: [0002] Drugs currently on the market for the treatment of cerebral embolism, cerebral vasospasm and other ischemic encephalopathy and cerebral arteriosclerosis diseases include flunarizine hydrochloride, hydrogenated ergot alkaloids, dihydroergotine mesylate, Xueshuantong, and cinnarizine , Betastine Oral Liquid, Papaverine Hydrochloride, Niacin Zantino Sodium Chloride Injection and other drugs for symptomatic treatment. On June 16, 2004, the State Intellectual Property Office published a patent application for "Ginkgo Dripping Pills for the Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases". The application number is 02135936, and the publication number is 1504208. For the problem...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/488A61K36/16A61K31/045A61K9/14A61K9/16A61K9/20A61K9/48A61P9/10
Inventor 陈兴莉杨建刚李萍王晓博
Owner TIANNING PHARMA OF SHAANXI PHARMA HLDG GROUP
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