Medicinal composition, and its preparing method and use

A technology of composition and medicine, which is applied in the field of pharmaceutical composition and its preparation, can solve the problems of unsatisfactory curative effect, unsatisfactory curative effect, and many side effects, and achieve the effects of no toxic side effects, high efficiency, and few side effects

Active Publication Date: 2008-02-27
CHENGDU DIAO JIU HONG PHARMACEUTICAL FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Though the existing Chinese patent medicine kind of multiple treatment hyperplasia of mammary glands is used for clinical selection at present, because the market demand of the medicine for the treatment of hyperplasia of mammary glands is very big, and western medicine treatment primary disease curative effect is not satisfactory, and side effect is more, existing Chinese medicine Although there are many kinds of patented medicines, most of them have unsatisfactory curative effects, which provides a huge market for the research and development of new Chinese patent medicine preparations for the treatment of mammary gland hyperplasia with definite curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The preparation of embodiment 1 medicament oral liquid of the present invention and the assay of ursolic acid

[0028] (1) preparation of medicament oral liquid of the present invention

[0029] a. Mix Cyperus Cyperi 250g, Curcuma 250g, Angelica 225g, Rhizoma Chuanxiong 200g, Qingpi 225g, Myrrh 125g, add water 14 times, soak overnight, distill and extract for 6 hours to get volatile oil;

[0030] b. Take another 375g of Prunella vulgaris, add 80% ethanol, reflux and extract twice, each time for 1 hour, filter, combine the alcohol extracts, recover ethanol, add 95% ethanol to the extract, reflux for half an hour, filter, and precipitate Wash with an appropriate amount of 95% ethanol, and recover the ethanol to obtain a refined extract.

[0031] c. Combine the above medicinal residues with the rest of the medicinal materials, add 7 times of water, decoct 3 times, 1 hour each time, combine the extracts, concentrate under reduced pressure to a relative density of 1.20 (40°...

Embodiment 2

[0039] Embodiment 2 Preparation process of pharmaceutical granules of the present invention

[0040] a. Weighing raw materials:

[0041] Prunella vulgaris 300g, Qingpi 180g, Cyperus cyperi 200g, Curcuma 200g, Fritillaria 180g, Paeoniae Alba 180g, Angelica 180g, Rhizoma Chuanxiong 160g, Myrrh 100g, Poria cocos 160g, Yuzhou leaking reed 160g, made into 1000g granules.

[0042] b. Preparation: Take the eleven traditional Chinese medicines in the prescription and add water to decoct three times. For the first time, use 10 times the amount of water to decoct for 1 hour; for the second time, use 5 times the amount of water to decoct for 0.5 hour; Decoction for 0.5 hours; combined decoction, filtered, concentrated under reduced pressure to a relative density of 1.20 (40°C), spray-dried the concentrated solution to obtain extract powder, mixed extract powder and dextrin in a ratio of 1:1, granulated, dried, Whole granules, get 1000g granules, pack separately, and get ready.

Embodiment 3

[0043] Embodiment 3 pharmaceutical tablet preparation process of the present invention

[0044] a. Weigh raw materials:

[0045] Prunella vulgaris 300g, Qingpi 180g, Rhizoma Cyperi 200g, Curcuma 200g, Fritillaria 180g, Paeoniae Alba 180g, Angelica 180g, Rhizoma Chuanxiong 160g, Myrrh 100g, Poria cocos 160g, Yuzhou leaking reed 160g; made into 1000g tablets.

[0046] b. Preparation: Take the eleven traditional Chinese medicines in the prescription and add water to decoct three times. For the first time, use 10 times the amount of water to decoct for 1 hour; for the second time, use 5 times the amount of water to decoct for 0.5 hour; Decoct for 0.5 hours; combine the decoctions, filter, concentrate under reduced pressure to a relative density of 1.20 (40°C), spray-dry the concentrated solution to obtain extract powder, press the extract powder into tablets to obtain 1000 tablets, and pack separately to obtain final product.

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PUM

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Abstract

The present invention provides a Chinese medicine composition for effectively curing hyperplasia of mammary glands with obvious therapeutic effect. Said medicine composition contains 11 Chinese medicinal materials of prunella spike, unripe tangerine peel, cyperus root, curcuma tuber, Zhejiang fritillaria bulb, white peony root, Chinese angelica root and others. Besides, said invention also provides its preparation method.

Description

technical field [0001] The invention relates to a pharmaceutical composition and its preparation method and application, in particular to a pharmaceutical composition prepared from traditional Chinese medicine as a raw material, its preparation method and application, and belongs to the field of medicine. Background technique [0002] Hyperplasia of mammary glands (hyperplasia of mammary glands) is the most common non-inflammatory disease of the breast. It is characterized by breast lumps, aggravation of premenstrual swelling and pain, and relief after menstruation. Clinically, hyperplasia of mammary glands is divided into three types: Breast pain, breast adenosis and breast cystic hyperplasia. Mammary gland hyperplasia is a common disease of adult women, frequently-occurring disease, accounts for about 15% of young and middle-aged women, and accounts for the first place of mammary gland diseases. According to the 10-year census data of the Breast Disease Treatment Group of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K36/8967A61K36/8905A61K36/71A61K36/536A61K36/328A61K36/28A61K36/232A61K36/076A61K9/16A61K9/20A61K9/48A61K9/10A61K9/08A61P15/14
Inventor 李伯刚刘瑜刘忠荣及元乔王若竹石金发何民
Owner CHENGDU DIAO JIU HONG PHARMACEUTICAL FACTORY
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