Medicine for treating gastric cavity pains, process for preparing the same and application thereof
A technology for epigastric pain and drugs, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., can solve the problems of small side effects, etc., and achieve the effects of less components, simple preparation process, and no residual toxicity of solvents
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Embodiment 1
[0038] The preparation of embodiment 1 medicine soft capsule
[0039] Wash 0.8kg of dried ginger and 2.4kg of galangal with clean water, then dry at 50°C, pulverize the dried ginger and galangal to 20 mesh fine powder, and grind the dried ginger powder and galangal Ginger powder is combined with the supercritical carbon dioxide fluid extraction device of 100ml-SPE manufactured by Hanwei (HANDWAY) company to extract lipophilic effective active substances. The extraction temperature is 45°C, the extraction pressure is 30mPa, and the extraction time is 2 hours; supercritical extraction The final medicinal residues are extracted by alcohol extraction and water precipitation method to extract hydrophilic effective active substances, the ethanol concentration is 75%, and the alcohol extraction temperature is 80°C. Concentrate the alcohol extract to a relative density of 1.2 (at 80°C), add 5.5 times the amount of water, stir well, let stand for 5 hours, filter, take the precipitate a...
Embodiment 2
[0040] The preparation of embodiment 2 medicine soft capsules
[0041] Wash 1.92kg of dried ginger and 1.28kg of galangal with clean water respectively, dry the dried ginger and galangal at 40°C respectively, grind the dried ginger and galangal into 20-mesh fine powder, and grind the The dried ginger powder and galangal powder combined and adopted the supercritical carbon dioxide fluid extraction device of 100ml-SPE manufactured by Hanwei (HANDWAY) company to extract lipophilic effective active substances. The extraction temperature is 50°C, the extraction pressure is 26mPa, and the extraction time is 2.2 hours; the medicinal dregs after supercritical extraction are extracted with alcohol extraction and water precipitation method to extract effective hydrophilic active substances, the ethanol concentration is 80%, and the alcohol extraction temperature is 70°C; the alcohol extract is concentrated to a relative density of 1.1 (80°C), Add 6 times the amount of water and stir wel...
Embodiment 3
[0042] The preparation of embodiment 3 medicine soft capsules
[0043] Wash 1.6kg of dried ginger and 1.6kg of galangal with clean water respectively, dry the dried ginger and galangal at 60°C respectively, grind the dried ginger and galangal into 20-mesh fine powder, and grind the The dried ginger powder and galangal powder combined and adopted the supercritical carbon dioxide fluid extraction device of 100ml-SPE manufactured by Hanwei (HANDWAY) company to extract lipophilic effective active substances. The extraction temperature is 47°C, the extraction pressure is 25mPa, and the extraction time is 1.9 hours; the medicinal dregs after supercritical extraction are extracted by alcohol extraction and water precipitation method, the effective hydrophilic active substance is extracted, the ethanol concentration is 75%, and the alcohol extraction temperature is 75°C. Concentrate the alcohol extract to a relative density of 1.0 (80°C), add 5 times the amount of water and stir well,...
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