Modified Monocytes/Macrophage Expressing Chimeric Antigen Receptors and Uses Thereof
a technology of chimeric antigen receptors and monocytes, which is applied in the direction of immunological disorders, drug compositions, peptides, etc., can solve the problems of limited car t cell efficacy in solid tumors (as well as in certain lymphoid tumors) and achieve the effect of stimulating an immune respons
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[0313]The invention is further described in detail by reference to the following experimental examples. These examples are provided for purposes of illustration only, and are not intended to be limiting unless otherwise specified. Thus, the invention should in no way be construed as being limited to the following examples, but rather, should be construed to encompass any and all variations which become evident as a result of the teaching provided herein.
[0314]Without further description, it is believed that one of ordinary skill in the art can, using the preceding description and the following illustrative examples, make and utilize the compounds of the present invention and practice the claimed methods. The following working examples therefore, specifically point out the preferred embodiments of the present invention, and are not to be construed as limiting in any way the remainder of the disclosure.
[0315]The materials and methods employed in these experiments are now described.
[03...
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