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Rotary platform type animals in-vivo multi-mode imaging detection system

An imaging detection and multi-mode imaging technology, applied in image enhancement, image analysis, image data processing, etc.

Inactive Publication Date: 2007-07-11
TSINGHUA UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The second is the detector, which is the core component of in vivo molecular image detection of small animals. At present, foreign high-sensitivity low-temperature refrigeration CCD detectors range from tens of thousands to hundreds of thousands of dollars, and only 3 foreign companies have mature products. ; The key issue in the third aspect is the optical system structure and lens. High-quality optical lenses with large numerical aperture and long working distance range from several thousand to more than ten thousand dollars. If you need to customize with a specific optical imaging system, a complete set Optical systems and lenses cost tens of thousands of dollars and are monopolized by Zeiss, Nikon and Leica

Method used

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  • Rotary platform type animals in-vivo multi-mode imaging detection system
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  • Rotary platform type animals in-vivo multi-mode imaging detection system

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Embodiment Construction

[0027] In order to achieve the above object, the present invention provides a rotating platform type small animal in vivo multi-mode hybrid imaging detection system, including a bipolar symmetrical nuclide (PET) imaging system, an infrared light transmission (or reflection) imaging system , a visible light (or fluorescence) transmission (or reflection) imaging system, an ultraviolet (or X-ray) transmission (or reflection) imaging system, a multi-axis motion controller (multi-axis controller for short) and a multi-channel signal processing device (referred to as multi-channel processor), and a rotating platform for placing small animals.

[0028] Said one bipolar symmetrical nuclide (PET) imaging system includes two crystal layers and two radiation detectors (PET detectors).

[0029] The infrared light transmission (or reflection) imaging system includes an infrared illumination source (or an infrared optical fiber array illumination source, or an infrared single optical fiber ...

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Abstract

The invention relates to a biological multimode picture detecting technique, wherein it comprises one PET shooting system with symmetry electrodes, one infrared transparent (reflective) shooting system, one visual light (or fluorescent) transparent (or reflective) shooting system, one ultraviolet (or X-ray) transparent (or reflective) shooting system, one rotation carrier of animal, multi-axle motion controller, multi-channel processor and computer. The carrier comprises one object platform, one frame, one constant-temperature controller, one rotator, and one XYZ three-dimension mover. The invention has multimode composition and 360degree scanning picture, with low cost.

Description

technical field [0001] The invention relates to small animal in vivo imaging detection technology and scientific instrument device structure, in particular to provide a small animal molecular image detection system and platform structure with a smart structure, low cost, and relatively high detection sensitivity and resolution. Background technique [0002] In vivo molecular imaging detection of small animals is a key link in the research of systems biology. It is also an intermediate bridge link for the transformation of scientific research and exploration from gene protein molecular level detection and cell level detection to clinical detection applications. In recent years, it has been published in Nature and Science. Nearly a hundred related articles reported the research results in this area. To carry out research work in this area, two types of instruments are inseparable. One is PET detection instruments, and the price of foreign products is more than 3 million → 5 mi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B6/00A61B5/00G06T5/00G06T7/00
Inventor 黄国亮白净单宝慈董洪莹
Owner TSINGHUA UNIV
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