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Heat clearing and detoxicating dispersant tablet and method for making same

A heat-clearing, detoxifying, and dispersible tablet technology, which is applied to medical preparations containing active ingredients, antiviral agents, and pharmaceutical formulas, can solve the problems of the lack of varieties of dispersible tablets of traditional Chinese medicine, the difficulty in controlling the disintegration speed of dispersible tablets of traditional Chinese medicine, and the high proportion of content. question

Inactive Publication Date: 2007-03-14
JIANGXI HERBFINE HI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Most of the traditional Chinese medicine dispersible tablets are difficult to control the disintegration speed of traditional Chinese medicine dispersible tablets within 3 minutes due to (1) the high proportion of main ingredients of traditional Chinese medicine, and (2) the adhesion of macromolecular substances such as pectin and polysaccharides. Western medicine dispersible tablets are more difficult to industrialize
There are many types of industrialized Western medicine dispersible tablets, but there are very few industrialized Chinese medicine dispersible tablets.

Method used

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  • Heat clearing and detoxicating dispersant tablet and method for making same
  • Heat clearing and detoxicating dispersant tablet and method for making same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The weight ratio of traditional Chinese medicine extract and auxiliary materials of Qingrejiedu dispersible tablet: 150g of fine powder of Qingrejiedu extract, 20g of micropowder silica gel, 75g of sodium carboxymethyl starch, 50g of microcrystalline cellulose, 8g of magnesium stearate, acesulfame K 7g.

[0029] The composition ratio of heat-clearing and detoxifying is recorded in the Chinese Pharmacopoeia: 670g of gypsum, 134g of honeysuckle, 107g of scrophulariaceae, 80g of rehmannia, 67g of forsythia, 67g of gardenia, 67g of sweet diding, 67g of scutellaria baicalensis, 67g of gentian, 67g of isatid root, and 54g of anemarrhena , Ophiopogon japonicus 54g.

[0030] Heat-clearing and detoxifying dispersible tablets are obtained according to the following specific steps: take gypsum, scrophulariae, rehmannia glutinosa, forsythia, gardenia, sweet diding, gentian, isatidis, anemarrhena, and radix ten herbs, soak them in water, and then decoct them. Boil twice, after boil...

Embodiment 2

[0033] Heat-clearing and detoxifying dispersible tablets: 150g fine powder of heat-clearing and detoxifying extract by weight, sodium carboxymethylcellulose 52g, microcrystalline cellulose 50g, cross-linked polyvinylpyrrolidone 26g, polyvinylpyrrolidone 28g, micropowdered silica gel 7g, twelve Alkyl magnesium sulfate 3g, citric acid 10g. All the other are with embodiment 1.

Embodiment 3

[0035] Heat-clearing and detoxifying dispersible tablets: 150g of fine powder of heat-clearing and detoxifying extract by weight ratio, 45g of croscarmellose sodium, 13g of cross-linked polyvinylpyrrolidone, 12g of low-substituted hydroxypropyl cellulose, 75g of pregelatinized starch, Mannitol 20g, calcium stearate 2g, magnesium stearate 3g. All the other are with embodiment 1.

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Abstract

The invention relates to dispersible tablets for heat clearing and detoxicating, as well as the preparing process, wherein the raw materials include gypsum, scrophularia root, dried rehmannia root, capsule of weeping forsythia, cape jasmine, Herba Corydalis bungeanae, rough gentian, isatic root, anemarrhena rhizome, lilyturf root, honeysuckle flower, and baikal skullcap root.

Description

technical field [0001] The invention relates to the technical field of Chinese patent medicine dispersible tablets, in particular to a heat-clearing and detoxifying dispersible tablet and a preparation method thereof. Background technique [0002] Dispersible tablets are a new drug dosage form developed in recent years. There are many dosage forms of heat-clearing and detoxifying drugs, which have the effect of clearing away heat and detoxifying. It is used for fever, flushed face, irritability and thirst, sore throat and other symptoms caused by excessive heat and toxin; influenza and upper respiratory infection see the above syndromes. The heat-clearing and detoxifying oral liquid, one of the original dosage forms, has been included in the 2005 edition of the Chinese Pharmacopoeia. Although the Qingrejiedu oral liquid is convenient to take, it has poor stability, inconvenient packaging, transportation and storage, and it is difficult to grasp the dosage. [0003] Compare...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/20A61P11/00A61P11/04A61P31/16A61K33/06
Inventor 罗晓健饶小勇何双凤王文
Owner JIANGXI HERBFINE HI TECH
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