Lung clearing cough suppressing phlegm transforming medicinal preparation and its new preparation method

A traditional Chinese medicine preparation, the technology of transforming tangerine red, applied in pill delivery, pharmaceutical formula, aerosol delivery, etc., can solve the problems of many impurities, affecting clinical application, and large dosage

Inactive Publication Date: 2006-08-30
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] The preparation method of dropping pill of the present invention:

[0067] prescription:

[0068] Scutellaria baicalensis 211g Cooked rhubarb 26g Anemarrhena 26g

[0069] Tianhua Fen 105.5g Ophiopogon japonicus 26g Tangerine 26g

[0070] Bitter almond (peeled and fried) 26g Morus almond (honey roasted) 53g Fritillaria 53g

[0071] Bellflower 53g Citrus aurantium (stir-fried with bran removed) 53g Licorice 6.5g

[0072] Qianhu 26g Baibu 26g

[0073] PEG4000 100g

[0074] Makes 1000 pills

[0075] Preparation:

[0076] (1) Take the three medicinal materials of Fructus Fructus Fructus Aurantii, Huajuhong and Peucedanum, and use supercritical extraction method (or steam distillation method): put the pulverized medicinal materials into a supercritical extraction kettle, when the extraction pressure is 20Pa, and the extraction temperature is 35°C, extract Time 1.0h, to get the extract; β-CD inclusion, the best process is: the ratio of water to oil to β-CD is 1:10, ultr...

Embodiment 2

[0081] The preparation method of soft capsule of the present invention:

[0082] prescription:

[0083] Scutellaria baicalensis 864g Cooked rhubarb 108g Anemarrhena 108g

[0084] Tianhua Fen 432g Ophiopogon japonicus 108g Tangerine 108g

[0085] Bitter almonds (peeled and fried) 108g Morus almonds (honey roasted) 216g Fritillaria 216g

[0086] Bellflower 216g Citrus aurantium (stir-fried with bran removed) 216g Licorice 27g

[0087] Qianhu 108g Baibu 108g

[0088] PEG400480g

[0089] Makes 1000 capsules

[0090] Preparation:

[0091] (1) Take the three medicinal materials of Fructus Fructus Fructus Aurantii, Huajuhong and Peucedanum, and use supercritical extraction method (or steam distillation method): put the pulverized medicinal materials into a supercritical extraction kettle, when the extraction pressure is 20Pa, and the extraction temperature is 35°C, extract Time 1.0h, to get the extract; β-CD inclusion, the best process is: the ratio of water to oil to β-CD is ...

Embodiment 3

[0096] The preparation method of granule of the present invention:

[0097] prescription:

[0098] Scutellaria baicalensis 576g Cooked rhubarb 72g Anemarrhena 72g

[0099] Tianhua Fen 288g Ophiopogon japonicus 72g Tangerine 72g

[0100] Bitter almond (peeled and fried) 72g Morus almond (honey roasted) 144g Fritillaria 144g

[0101] Bellflower 144g Citrus aurantium (stir-fried with bran removed) 144g Licorice 18g

[0102] Qianhu 72g Baibu 72g

[0103] Made into 1000g

[0104] Preparation:

[0105] (1) Take the four medicinal materials of Fructus aurantii Fructus Fructus Aurantii, Huajuhong, Peucedanum Peucedanum and Trichosanthes Fructus Folium, and make powder into medicine;

[0106] (2) Get Platycodon grandiflorum and Ophiopogon japonicus, extract twice with 4 times the amount of methanol, reclaim the extract, dissolve the concentrate in a small amount of methanol, pour it into acetone, filter with suction, and reclaim the filtrate;

[0107] (3) Take the remaining medi...

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PUM

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Abstract

A composite Chinese medicine in the form of dripping pill and soft capsule for treating cough with yellow sputum, suffocative feeling in chest and hypochondrium, sore throat, hoarsenes and dry stools, and its preparing process are disclosed.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription and a preparation process thereof for coughing with yellow phlegm caused by lung-heat phlegm, poor chest and diaphragm, sore throat and hoarse voice, and dry stool. Background technique: [0002] Cough with yellow phlegm caused by lung-heat phlegm, poor chest and diaphragm, sore throat and hoarseness, and dry stool are common clinical symptoms. Traditional Chinese medicine often adopts the methods of clearing the lung, resolving phlegm, and relieving cough, and the curative effect is remarkable. Qingjin Zhisou Huatan Wan is its representative drug. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction proc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/06A61K9/16A61K9/20A61K9/48A61P11/14A61P11/10
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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