Preparation technology of mammary healthy dispersion tablet

A preparation process, a technology for dispersible tablets, which is applied in the field of preparation of Rukang dispersible tablets obtained by changing the dosage form of Rukang Tablets. It can solve the problems of no proof of the positive effect of adding excipients, no ratio and parameters given, and failure to disintegrate. To achieve the effect of treating mammary gland hyperplasia, reliable curative effect and quick onset

Inactive Publication Date: 2006-06-14
高铁成
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  • Summary
  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

However, the proportion and parameters of adding the above-mentioned materials are not given, and the positive effect brought by the addition of excipients is not proved. Those skilled in the art cannot obtain the real fast disintegration and recovery mentioned in the specification from the technical solution of the application. Features of quick effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Rukang Dispersible Tablets per 1000 prescription:

[0026] Chinese medicine raw materials: 75g oyster, 30g frankincense, 75g melon wilt, 60g seaweed, 120g astragalus, 30g myrrh, 60g asparagus, 75g prunella vulgaris, 30g trigonum, 60g scrophulariaceae, 60g Atractylodes macrocephala, 30g fritillaria, 30g zedoary, Salvia miltiorrhiza 75g, fried chicken inner gold 30g;

[0027] Excipients: cross-linked PVP 100g, CMS-Na 100g, microcrystalline cellulose 140g, magnesium stearate 4g, micropowder silica gel 4g, aspartame 10g;

[0028] The preparation process comprises the following steps:

[0029] Grind the above 15 traditional Chinese medicine raw materials, among which the fried chicken neijin, Zhejiang Fritillaria, frankincense, and myrrh are crushed into fine powder, and the remaining 11 flavors are decocted twice, and the first time adding water is 12 times the amount of traditional Chinese medicine raw materials , adding water for the second time is 10 times the amount o...

Embodiment 2

[0034] Every 1000 prescriptions of Kangdispersible tablets: the raw materials of Chinese medicine are the same as in Example 1. Excipients: 50g of cross-linked PVP, 180g of CMS-Na, 110g of microcrystalline cellulose, 2g of magnesium stearate, 8g of micropowdered silica gel, 4g of aspartame, 6g of stevia; appropriate amount of orange essence. The preparation process is the same as in Example 1.

Embodiment 3

[0036] Every 1000 prescriptions of Rukang Dispersible Tablets: Chinese medicine raw materials are the same as in Example 1. Excipients: 160g cross-linked PVP, 60g CMS-Na, 120g microcrystalline cellulose, 6g magnesium stearate, 25g micronized silica gel, 13g aspartame; 6g citric acid, appropriate amount of strawberry essence. The preparation process is the same as in Example 1.

[0037] 1. Source of prescription

[0038] The prescription of Rukang Dispersible Tablets prepared by the present invention comes from the twelfth volume of traditional Chinese medicine preparations in "Drug Standards of the Ministry of Health", standard number: WS 3 - Prescription for Rukang Tablets for B-2356-97. The invention is a new drug variety improved from a tablet to a dispersible tablet, which better exerts the performance of the drug and is convenient for more patients to take, and at the same time adds a new option for clinical medication.

[0039] 2. Prescription amount and dosage of Ruk...

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Abstract

A Chinese medicine í‹Rukang dispersing tabletíŒ for treating mastoplasia is an improvement to í‹Rukang tabletíŒ and is prepared from the raw materials of í‹Rukang tabletíŒ and additional additives. Its advantages are high disintegrating and dissolving speed, good dispersed state and quickly taking its effect. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a preparation method of traditional Chinese medicine dispersible tablets, in particular to a preparation method of Rukang dispersible tablets obtained by changing the dosage form of Rukang tablets. The Rukang dispersible tablet prepared by the method has the characteristics of fast disintegration and quick onset of action, and can be disintegrated within 3 minutes after being swallowed or soaked in warm boiled water to exert the medicinal effect. Background technique [0002] Breast hyperplasia is a common and frequently-occurring disease in women. On one or both sides of the breast, the patient can feel lumps of different sizes, soft and hard, and unclear boundaries. There seem to be small particles on the surface, which have no adhesion to the skin and fascia. They feel pain after pressing with fingers. Accompanied by distending pain or soreness of the breast at the same time, individual patients al...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/20A61K35/57A61P15/14
Inventor 高铁成
Owner 高铁成
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