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Application of medicinal composition contg. red lady-slipper for preparing medicine of anti-aspirin-resistance

A technology of aspirin and composition, applied in the application of anti-aspirin-resistance drugs, in the field of medicinal compositions containing red peony root, can solve problems such as aspirin-resistance and the like

Inactive Publication Date: 2006-01-25
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to alleviate the phenomenon of aspirin resistance that occurs when cardiovascular and cerebrovascular patients use aspirin drugs to treat cardiovascular and cerebrovascular diseases, some scientific researchers are currently looking for drugs that can replace or alleviate the phenomenon of aspirin resistance. Some drugs are tested in order to find new uses of their drugs to solve the phenomenon of aspirin resistance caused by current aspirin use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Take 100g of salvia miltiorrhiza, 100g of chuanxiong, 200g of red peony, 80g of safflower, 80g of angelica, 80g of heterophylla, 80g of scallion, 80g of gualou skin, 60g of polygala, 60g of Jiangxiang, 60g of shichangpu, and 60g of licorice;

[0050] The above twelve flavors, 50g each of Ligusticum Chuanxiong and Radix Paeoniae Rubra, are crushed into fine powder, sieved, and the rest is crushed; soak the safflower twice in warm water at 75°C for 2 hours each time, combine the soaking liquid, filter, and concentrate the filtrate to a thick paste; Jiangxiang is crushed into a coarse powder, and after extracting the volatile oil, the residue is decocted with other eight flavors such as Salvia miltiorrhiza, broken Rhizoma Chuanxiong and Radix Paeoniae Rubra, and boiled twice with water for 3 hours each time, and the decoction is combined and filtered. Concentrate the filtrate to a clear paste with a relative density of 1.40 (thermal measurement), add the above-mentioned fin...

Embodiment 2

[0052] Take 200g of salvia miltiorrhiza, 200g of Chuanxiong, 400g of red peony, 40g of safflower, 40g of angelica, 40g of heterophylla, 40g of scallion, 40g of melon skin, 30g of Polygala, 30g of Jiangxiang, 30g of Shichangpu, and 30g of licorice;

[0053] The above twelve flavors, 50g each of Ligusticum Chuanxiong and Radix Paeoniae Rubra, are crushed into fine powder, sieved, and the rest is crushed; the safflower is dipped in warm water at 65°C twice, each time for 2.5 hours, combined with the infusion, filtered, and the filtrate is concentrated to a thick paste; Jiangxiang is crushed into a coarse powder, and after extracting the volatile oil, the residue is decocted with other eight flavors such as Salvia miltiorrhiza, broken Rhizoma Chuanxiong and Radix Paeoniae Rubra, and boiled twice with water for 3 hours each time, and the decoction is combined and filtered. Concentrate the filtrate to a clear paste with a relative density of 1.30 (thermal measurement), add the above-...

Embodiment 3

[0055]Take 50g of salvia miltiorrhiza, 50g of Chuanxiong, 100g of red peony, 160g of safflower, 160g of angelica, 160g of heterophylla, 160g of scallion, 160g of melon peel, 120g of polygala, 120g of jiangxiang, 120g of shichangpu, and 120g of licorice;

[0056] The above twelve flavors, 35g each of Ligusticum Chuanxiong and Radix Paeoniae Rubra, are crushed into fine powder, sieved, and the rest is broken as appropriate; the safflower is soaked twice in 50C warm water, each time for 3 hours, combined with the soaking liquid, filtered, and the filtrate is concentrated to Thick paste; Jiangxiang is crushed into a coarse powder, after extracting the volatile oil, the residue is decocted with other eight flavors such as Salvia miltiorrhiza and broken Rhizoma Chuanxiong and Radix Paeoniae Rubra, with water for 2 hours each time, and the decoction is combined, filtered, and the filtrate Concentrated to a clear paste with a relative density of 1.15-1.45 (thermal measurement), add the...

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Abstract

A Chinese medicine for treating the aspirin-resistant cardiovascular disease is prepared from 12 Chinese-medicinal materials including red sage root, Chuanxiong rhizome, red peony root, safflower, etc.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of a medicinal composition containing Radix Paeoniae Rubra in anti-aspirin resistance drugs. Background technique [0002] Aspirin, also known as aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth study of prostaglandins, a new understanding of aspirin has emerged: in addition to traditionally used for antipyretic, analgesic, and anti-inflammatory clinically, it is also used for anti-platelet aggregation and so on. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when aspirin i...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/00A61P9/10
Inventor 李永强郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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