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Application of medicine used in anti-aspirin-resistance medicine

A technology of aspirin and medicine, which is applied in the application field of pharmaceutical composition in anti-aspirin resistance drugs, and can solve problems such as aspirin resistance

Inactive Publication Date: 2006-01-25
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to alleviate the phenomenon of aspirin resistance that occurs when cardiovascular and cerebrovascular patients use aspirin drugs to treat cardiovascular and cerebrovascular diseases, some scientific researchers are currently looking for drugs that can replace or alleviate the phenomenon of aspirin resistance. Some drugs are tested in order to find new uses of their drugs to solve the phenomenon of aspirin resistance caused by current aspirin use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Take 500g of salvia miltiorrhiza, 500g of chuanxiong, and 500g of kudzu root for later use;

[0052] For the above three flavors, add water and decoct twice, the first time is 1.5 hours, and the second time is 1 hour, combine the decoction, filter, the filtrate is concentrated to a relative density of 1.08, filter while hot, and the filtrate is concentrated to a relative density of 1.38-1.40 Clear paste, add appropriate amount of sucrose powder, make granules, and dry at low temperature to make 1000g.

Embodiment 2

[0054] Take 500g of Salvia miltiorrhiza, 500g of Chuanxiong, and 500g of kudzu root for later use; add water to decoct the above three flavors twice, for 1.5 hours for the first time, and 1 hour for the second time, combine the decoctions, filter, and concentrate the filtrate to a relative density of 1.18-1.22 (50°C ), let it cool, add ethanol to make the alcohol content reach 65%; refrigerate for 48 hours, filter, recover the ethanol from the filtrate until it has no alcohol smell, and concentrate to a relative density of 1.10-1.14 (50°C), add 350ml of simple syrup, Potassium acid 1.8g, adjust the total amount to 1000ml, stir evenly, let stand, potting, and sterilizing, to obtain.

Embodiment 3

[0056] Take 300g of salvia miltiorrhiza, 300g of chuanxiong, and 800g of kudzu root;

[0057] The above three flavors are decocted twice with water, the first time is 4 hours, the second time is 2 hours, the decoction is combined, filtered, the filtrate is concentrated to a relative density of 1.05-1.22 (60°C), let it cool, and add ethanol to reduce the alcohol content. reach 55%; refrigerate for 36 hours, filter, and recover the ethanol from the filtrate until there is no alcohol smell, and concentrate to a relative density of 1.05-1.20 (50°C), add 250ml of simple syrup, 1.0g of potassium sorbate, adjust the total amount to 1000ml, Stir well, let it stand, potting, sterilizing, and you get it.

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PUM

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Abstract

A Chinese medicine for treating the aspirin-resistant cardiovascular disease is prepared from red sage root, Chuanxiong rhizome and kudzu vine root.

Description

technical field [0001] The invention relates to the field of medicine, in particular, the invention relates to the application of a pharmaceutical composition in anti-aspirin resistance drugs. Background technique [0002] Aspirin, also known as aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth study of prostaglandins, a new understanding of aspirin has emerged: in addition to traditionally used for antipyretic, analgesic, and anti-inflammatory clinically, it is also used for anti-platelet aggregation and so on. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at present, when aspirin is used...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K36/23A61K36/488A61K9/00A61P9/10
Inventor 李永强郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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