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Application of gentiopicrin in preparing medication for restraining hepatitis B virus

A technology of hepatitis B virus and gentiopicroside, which is applied in the direction of antiviral agents, drug combinations, and pharmaceutical formulas, and can solve problems such as slow effect, high recurrence rate, and uncertain curative effect

Inactive Publication Date: 2005-08-31
HARBIN GLORIA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, Western medicine has certain effects on the treatment of hepatitis B, but it has the disadvantages of large toxic and side effects and high recurrence rate.
The effect of traditional Chinese medicine treatment is slow. It takes a month or even a few months to feel whether it is effective. The medication cycle is very long. Some patients take the medicine for several years. Long-term medication is very irritating to the stomach. Many patients lose their diet and lose weight. curative effect is uncertain

Method used

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  • Application of gentiopicrin in preparing medication for restraining hepatitis B virus
  • Application of gentiopicrin in preparing medication for restraining hepatitis B virus
  • Application of gentiopicrin in preparing medication for restraining hepatitis B virus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The pharmaceutical preparation gentiopicroside is prepared into tablets, taking the production of 1000 tablets as an example, the raw materials and auxiliary materials and their weight ratios are as follows:

[0018] Gentiopicroside 200g

[0019] Starch 100g

[0020] Its preparation process is carried out according to the conventional process of pharmacy tablets, each tablet weighs 0.3g, and each tablet contains gentiopicroside 200mg.

[0021] Dosage: Take orally, 1 tablet each time, once a day, reduce as appropriate for children, 30 days is a course of treatment.

Embodiment 2

[0023] The medicinal preparation gentiopicroside is prepared into capsules, taking the production of 1000 capsules as an example, the raw materials and auxiliary materials and their weight ratios are as follows:

[0024] Gentiopicroside 200g

[0025] Starch 100g

[0026] Its preparation process is carried out according to the conventional process of pharmaceutical capsules, each capsule weighs 0.3g, and each capsule contains 200mg of gentiopicroside.

[0027] Usage and dosage: take orally, 1 capsule each time, once a day, reduce it for children. 30 days is a course of treatment.

Embodiment 3

[0029] The medicinal preparation gentiopicroside is prepared into granules, taking the production of 1000g of granule products as an example, the raw materials and auxiliary materials and their weight ratios are as follows:

[0030] Gentiopicroside 200g

[0031] Sucrose 400g

[0032] Dextrin 400g

[0033] The preparation process is carried out according to the conventional process of pharmacy granules, each bag weighs 1g, and 1g contains gentiopicroside 200mg.

[0034] Usage and dosage: Take orally, 1 bag each time, once a day, reduce it for children. 30 days is a course of treatment.

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Abstract

An application of gentiopicroside in preparing the medicine with it in conjunction of pharmacologically acceptable carrier for suppressing HBV is disclosed. It may be tablet, capsule, powder, pill, particle, or injection.

Description

technical field [0001] The invention relates to the new application of gentiopicroside for inhibiting hepatitis B virus in the body. Background technique [0002] The treatment of viral diseases has always been a difficult problem in the medical field. Although human beings defeated infectious diseases caused by bacteria in the nineteenth century, diseases caused by viral infections, such as AIDS, SARS, influenza, hepatitis B, meningitis, myocarditis, herpes zoster, etc., have not been cured so far. Fang, has been in the process of exploration. [0003] More prominent is hepatitis B. my country is the largest hepatitis country in the world. There are about 200 million virus carriers, about 120 million patients, and about 40 million hospitalized patients, which has aroused widespread concern in the medical field. [0004] The treatment of hepatitis B is divided into three aspects: inhibiting the virus, protecting the liver and promoting gallbladder, and reducing enzymes. T...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61P1/16A61P31/14
Inventor 孙文基尚平平
Owner HARBIN GLORIA PHARMA
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