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Nanometer compound Chinese medicinal formulation for treating chronic atrophic gastritis and its preparing method

A technology for atrophic gastritis and compound preparations, which are applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and drug delivery, can solve the problems of intractable cure, easy relapse of the disease, slow curative effect, etc. The effect of shrinking and patient convenience

Inactive Publication Date: 2005-04-20
武兴战
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Similar Chinese medicines of the same sex produced in China are mainly used for antibacterial, anti-inflammatory, analgesic, hemostatic and other effects. They are used for stomach heat and sore tongue, etc. They all have slow curative effects. Among similar Chinese patent medicines, "Mo Luo Dan" and "Wei Shu Granules" etc. have a certain effect on atrophic gastritis, and have the function of relieving and improving, but the disease is prone to relapse, that is, it is difficult to cure the disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take 60 grams of Maple Leaf, 50 grams of Dendrobium, 50 grams of Anemarrhena, 50 grams of Licorice, 50 grams of Coptidis, 50 grams of Sophora, 40 grams of Huoxiang, 40 grams of Lycium barbarum, 40 grams of Astragalus, 40 grams of Forsythia, 40 grams of Atractylodes macrocephala, Poria cocos 40 grams, 40 grams of purslane, 35 grams of rehmannia. Soak and dissolve the raw materials of the above-mentioned Chinese herbal medicines in warm water at 30°C-50°C, separate and extract the harmful properties of the medicines, and then extract them with warm fire to 80°C-90°C for 3 hours, and decoct them in water for 2 hours. Hours, add three times the amount of ethanol to filter. Collect the ethanol until dry, concentrate the paste with a relative density of 1.3-1.5 and dry it, and make a Chinese patent medicine with nano-chitosan and modified starch coating.

Embodiment 2

[0028] Take 100 maple leaves, 100 dendrobium, 100 anemarrhena, 100 licorice, 100 coptis, 100 flavescens, 80 wolfberry, 80 astragalus, 80 forsythia, 80 atractylodes, 80 poria, 80 purslane, and 60 rehmannia. Soak and dissolve the above-mentioned raw materials of various Chinese herbal medicines in warm water at 40°C, separate and extract the harmful properties of the medicines, dry and pulverize them, put the Chinese medicine preparations in the reaction extraction kettle, add process solvents, introduce microwave extraction, and design the polarity change motion speed It is 2 billion times per second, the temperature is controlled at 50°C, and the time is 360 minutes. Using the small molecule effect of the nanostructure, the active ingredients of the medicinal materials are promoted to undergo significant changes in biological activity, and the material particles are processed into ultrafine powders with a size of less than 80nm for pharmacological extraction of traditional Chine...

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Abstract

Said invention relates to a nano grade compound Chinese herbs for treating atrophic gastritis and preparation thereof, which adopt the nano structured drug compatibility technology, greatest utilization of pharmacody, optimized compatible biological activity effective content, and has good cure effect to superficial gastritis, gland atrophy, heterotype hyperplasia, reversion canceration treatment. The formula is (by weight) 30-130 of maple leaf, 40-130 of dendorbium stem, 40-130 of anemarrhena, 50-130 of liquorice etc 14 kinds of herbs.

Description

1. Technical field: [0001] The invention relates to a nanoscale traditional Chinese medicine compound preparation for treating atrophic gastritis and a preparation method thereof. 2. Background technology: [0002] Similar Chinese medicines of the same sex produced in China are mainly used for antibacterial, anti-inflammatory, analgesic, hemostatic and other effects. They are used for stomach heat and sore tongue, etc. They all have slow curative effects. Among similar Chinese patent medicines, "Mo Luo Dan" and "Wei Shu Granules" etc. have a certain effect on atrophic gastritis, and have the function of relieving and improving, but the disease is prone to relapse, that is, it is difficult to cure the disease. 3. Contents of the invention: [0003] In order to solve the deficiencies in the above-mentioned background technology, the present invention provides a nanoscale traditional Chinese medicine compound preparation for treating atrophic gastritis and a preparation metho...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K9/14A61P11/02
Inventor 武兴战
Owner 武兴战
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