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Ainsliaca fragrans dripping pill and its preparing method

A technology of apricot-flavored rabbit ears and dropping pills, which is applied in the fields of pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve problems such as slow onset of action, low bioavailability, and slow disintegration

Inactive Publication Date: 2005-03-02
JIANGXI HERBI SKY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are Xingxiang Tuerfeng Tablets on the market. This dosage form disintegrates slowly, has poor dissolution, slow onset of action, and low bioavailability.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Example 1: Xingxiang Rabbit Ear Wind 3000g

[0010] Polyethylene glycol (6000) 150g

[0011] Poloxamer (188) 25g

[0012] Preparation method of apricot rabbit ear wind extract: take apricot rabbit ear wind medicinal material, soak in water, add 3-8 times the weight of the medicinal material, decoct, filter for 2 hours for the first time, add 3-8 times the drug dregs for the second time The amount of water, boiled for 2 hours, filtered, the third time add 3-8 times the amount of water, boiled for 2 hours, combined decoction liquid, filtered, and the filtrate was concentrated under normal pressure or reduced pressure until the relative density was 1.1~ 1.2 (60°C) clear ointment, add ethanol to make the alcohol content reach 70%, let it stand for 24 hours, separate the supernatant, wash the precipitate twice with 70% ethanol, each time with the same amount of ethanol, wash solution Combine with the supernatant, recover ethanol, concentrate under reduced...

Embodiment 2

[0014] Example 2: Xingxiang Rabbit Ear Wind 4000g

[0015] Polyethylene glycol (6000) 190g

[0016] The preparation method of the extract of Apricot Fragrant Rabbit Ear Wind is the same as in Example 1.

[0017] Heat polyethylene glycol 6000 190g on a water bath to melt it; add Xingxiang Rabbit Ear Wind Thick Cream, stir evenly, and keep warm at 95°C for later use; preheat the dropping pill machine, and keep the temperature of the liquid storage room at 95±2°C The coolant simethicone is pre-cooled to 10-12°C, adjust the distance between the drip nozzle and the coolant surface, pour the liquid medicine into the liquid storage chamber, start the valve, and drop the medicine liquid into the coolant drop by drop at a speed of about 80-95 drops / minute, open the valve of the collection port, collect the dripping pills, filter the coolant with gauze, and absorb the residual oil stains on the surface, spread it out, and dry it to obtain the shaped dropping pills.

Embodiment 3

[0018] Example 3: Xingxiang Rabbit Ear Wind 2000g

[0019] Polyethylene glycol (4000) 120g

[0020] The preparation method of the extract of Apricot Fragrant Rabbit Ear Wind is the same as in Example 1.

[0021] Obtain Xingxiang Tuerfeng Dripping Pills by Example 2.

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PUM

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Abstract

The ainsliaea fragrans dripping pill of the present invention includes ainsliaea fragrans extract in recipe amount and medicinal supplementary material. The medicinal supplementary material includes polyglycol, polyoxyethylene stearate ester, sodium stearate, glyceric acid, urea and poloxamer. Compared with other preparation form, the dripping pill of the present invention has the advantages of fast acting, high bioavailability, simple production process, etc.

Description

technical field [0001] The invention relates to an oral dripping pill made from apricot-flavored rabbit's ear wind as a main raw material and a preparation method thereof. Background technique [0002] Apricot Fragrant Rabbit Ear Wind is a genuine medicinal material in Jiangxi, which contains saponins, alkaloids, phenols, and flavonoids; it has the effects of clearing away heat, detoxification, dampness, and hemostasis. It has a unique curative effect on menstruation, postpartum lochia, and blood stasis. Apply modern technology to make it into drop pills, which can treat leucorrhea, cervicitis, dysmenorrhea, mastitis, regulate menstruation and reduce inflammation. It is a good medicine for gynecology. [0003] At present, there are Xingxiang Tuerfeng Tablets on the market, which have slow disintegration, poor dissolution, slow onset of action and low bioavailability. The Xingxiang Rabbit's Ear Wind is made into a drop pill, which can achieve quick-acting, high-efficiency, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P15/00A61P15/14
Inventor 吴朝阳黄小兰徐发红黄经球陈科茂
Owner JIANGXI HERBI SKY CO LTD
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