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Novel preparation method of

A preparation process and technology of Rehmannia glutinosa are applied in the preparation process of Mingmu Dihuangxin and the field of preparation thereof, which can solve the problems of lack of modernization of traditional Chinese medicine preparations, slow dissolving and dispersing of concentrated pills, low bioavailability, etc. Convenience and small dosage

Inactive Publication Date: 2005-01-19
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The prescription amount of the concentrated pill is reduced by about one-third on the basis of the pill, and 8-10 pills still need to be taken each time, and the volatile components are easily lost during the concentration and drying process, and the concentrated pill is also dissolved. Slow, low bioavailability
[0004] To sum up, the existing Mingmu Rehmannia preparations can not only fully retain the active ingredients of the prescription Chinese medicinal materials to ensure the curative effect, but also achieve exquisite preparations and small dosages, which can fully reflect the modernization of traditional Chinese medicine preparations.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Example 1: Preparation of Mingmu Dihuang Capsules

[0038] Separately select twelve medicinal herbs, remove impurities, and pass the test for later use; crush Cassia chinensis into fine powder for later use; the remaining eleven medicinal herbs are respectively crushed into coarse powder for later use; take Moutan cortex, chrysanthemum, and angelica, add water to distill and extract Volatile components are dissolved with an appropriate amount of absolute ethanol for later use; the distilled aqueous solution is ultrafiltered for later use; dogwood, medlar, white peony root, and tribulus are extracted twice with 70% ethanol, and the extracts are combined, ultrafiltered, and ethanol is recovered from the filtrate for later use; Poria cocos Soak in warm water for 2 times, combine the extracts, ultra-filter, and use the filtrate for later use; add rehmannia glutinosa, yam, and Alisma, add water and decoct 3 times, the first and second times are 2 hours each, and the third tim...

Embodiment 2

[0039] Example 2: Preparation of Mingmu Dihuang Capsules

[0040] The twelve medicinals are selected separately, and impurities are removed, and the inspection is qualified for later use; the twelve medicinals in the prescription are respectively crushed into coarse powder for later use; the cortex of Moutan, chrysanthemum, and angelica are respectively distilled with water, and the volatile components are extracted to make-environmental Dextrin inclusion compound for standby; distilled aqueous solution for ultrafiltration for standby; medicinal dregs, rehmannia glutinosa, Alisma, dogwood, medlar, white peony root, Tribulus terrestris, and Alisma are extracted twice with 90% ethanol, and the extracts are combined and ultrafiltered , the filtrate recovered ethanol for later use; Poria cocos was soaked in warm water for 2 times, the leachate was combined, ultrafiltered, and the filtrate was used for later use; Chinese yam was decocted with water for 3 times, the first and second ti...

Embodiment 3

[0041] Example 3: Preparation of Mingmu Dihuang Tablets

[0042] Separately select twelve medicinal herbs, remove impurities, and pass the inspection for later use; crush Cassia chinensis into fine powder for later use; the remaining eleven medicinal herbs are respectively crushed into coarse powder for later use; take Moutan bark, chrysanthemum, and angelica, add water and distill under reduced pressure respectively , extract the volatile components, and dissolve them with an appropriate amount of absolute ethanol for later use; the distilled aqueous solution is filtered for later use; the medicinal residues of dogwood, medlar, white peony root, tribulus and the above-mentioned peony cortex and chrysanthemum are extracted twice with 90% ethanol, and the combined extraction liquid, filtered, and the filtrate recovered ethanol for later use; Poria cocos was soaked in warm water for 2 times, the leachate was filtered, and the filtrate was used for later use; Rehmannia glutinosa, ...

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Abstract

The invention discloses a novel preparation method of 'Mingmu Dihuang' and its formulation, characterized by the modification to the preparing process by using the novel medicament preparing technologies, which achieves the beneficial effects of good curative effect, small amount of administration and easiness in carrying. The preparation can be used for treating photophobia and irritated epiphora with warm tear.

Description

technical field [0001] The invention relates to the technical field of Chinese patent medicine preparation technology, in particular to the preparation technology of Mingmu Rehmannia glutinosa and its preparation. Background technique [0002] Mingmu Dihuang Pills came out of "All Diseases Rejuvenating Spring" in the Ming Dynasty. It is composed of Liuwei Dihuang Pills plus medlar, chrysanthemum, angelica, white peony root, terrestris, and cassia. It is a famous ophthalmology prescription in traditional Chinese medicine. Function, it is effective for liver and kidney yin deficiency, astringent eyes, photophobia, blurred vision, wind and tears embolism. The process of the pill is that the twelve medicinal materials in the prescription are crushed into fine powder, and an appropriate amount of refined honey / honey water is added to make a large honeyed pill / water honeyed pill. Because all the raw powders of the traditional Chinese medicines in the presc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/28A61K9/48A61P1/14A61P27/02
Inventor 毛友昌毛小敏
Owner 毛友昌
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