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Medicine for treating chronic prostatitis and its preparing method

A chronic prostatitis and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2005-01-12
吉林省银诺克药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The invention provides a medicine for treating chronic prostatitis and a preparation method thereof, so as to solve the current problems in the treatment of prostatitis in the convalescent period, to consolidate the curative effect and prevent recurrence

Method used

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  • Medicine for treating chronic prostatitis and its preparing method
  • Medicine for treating chronic prostatitis and its preparing method
  • Medicine for treating chronic prostatitis and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0037] Experimental Example 1: Effect of Qianlie Kangshu Capsules on Permeability of Mouse Peritoneal Capillaries

[0038] The test mice were randomly divided into four groups: control (distilled water 20ml / kg); aspirin (0.5g / kg); high-dose (4g / kg) and low-dose Qianliekangshu (2g / kg), 10 in each group, every day Oral administration once in the morning, for four consecutive days, 30 minutes after the last administration, each mouse was injected with 0.5% Evans blue 0.1ml / 10g body weight through the tail vein, and then intraperitoneally injected 0.6% glacial acetic acid 0.1ml / 10g body weight, After 20 minutes, the mice were sacrificed by devertebralization, the abdominal cavity was cut open, and the abdominal cavity was washed four times with 3ml of normal saline, combined with the four washes, added to 10ml of normal saline, centrifuged at 3000rpm for 15min, and the supernatant was washed with 7550 UV-visible light intensity. The meter was used for colorimetry at a wavelength o...

experiment example 2

[0049] Experimental Example 2: Effect of Qianlie Kangshu Capsules on Paw Swelling in Rats Induced by Carrageenan

[0050] The test mice were randomly divided into four groups of blank control (distilled water 10ml / kg), aspirin (0.1g / kg), high dose (2g / kg) and low dose Qianlie Kangshu (1g / kg), 10 in each group, Oral administration once a day for five consecutive days. After the last administration, the normal volume of the right paw of each rat was recorded respectively. One hour later, 0.1ml of 1% carrageenan was injected into the skin of the right paw. 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours of foot plantar volume after recording the inflammation, compare the change of its volume (i.e. swelling degree) before and after the administration, and calculate the swelling percentage and swelling inhibition percentage according to the following formula, Statistical analysis of differences between groups was performed using t-test.

[0051]

[0052]

[0053] Results and ...

experiment example 3

[0079] Experimental Example 3: Effect of Qianlie Kangshu on Cotton Ball Granuloma in Rats

[0080] Forty rats were randomly divided into four groups: normal control, aspirin, high-dose and low-dose Qianliekangshu, with 10 rats in each group. Rats in each group were made abdominal incisions under light ether anesthesia, and implanted subcutaneously in the axillae on both sides. A 50 mg cotton ball (sterilized by autoclaving, plus penicillin 0.1ml / 10mg, dried at 60°C) was given by intragastric administration on the second day after the operation (see Table 3 for dosage). Once a day, administered continuously for seven days, the rats were decapitated on the eighth day after weighing, the cotton ball granulation tissue was stripped and taken out, dried in an oven at 80°C for 1 hour, and weighed with a precision microelectronic balance after taking it out , minus the weight of the original cotton ball, that is the net weight of granuloma, expressed in milligrams of granuloma per 10...

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Abstract

A Chinese medicine for treating chronic prostatitis is prepared from 7 Chinese-medicinal materials including giant knotweed rhizome, turtle shell, astragalus root, wolfberry fruit, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a medicine for treating chronic prostatitis and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Chronic prostatitis is a clinical common disease, frequently-occurring disease. Especially young adults have a higher incidence, accounting for about 35-40% of young males. In recent years, due to the specific historical and social environment, the incidence has been increasing year by year. The patient's illness seriously affects the patient's physical and mental health and work. Especially serious medical records are often combined with sexual dysfunction, which affects fertility, family and married life, etc., and has an impact on individuals, families and society. [0003] Since the 1970s, this disease has been systematically studied in China, especially the research on the etiology and pathogenesis of this disease is more prominent, and the damp heat in the lo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/586A61P13/08
Inventor 王少金
Owner 吉林省银诺克药业有限公司
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