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Contact lens solution

A technology for contact lenses and liquids, applied in detergent compositions, detergent compounding agents, glasses/goggles, etc., and can solve problems such as lack of practicality, eye damage, etc.

Inactive Publication Date: 2004-05-19
OPHTECS CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no record of any damage to the eyes caused by a large amount of polylysine adsorbed on group 4 lenses and wearing a group 4 lens with a large amount of polylysine adsorbed
And this problem is very significant when actually wearing a contact lens, so the above-mentioned various prior art lacks practicability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Solutions 1-3 and comparative solutions 1-3 were prepared according to the compositions shown in Table 1 below. And use hydrochloric acid or sodium hydroxide pH adjuster to adjust the pH value of each solution and comparison solution.

[0038] Table 1

[0039] The unit is (w / v%) (except polyhexamethylene biguanide and pH value)

[0040] Element

[0041] Using Solution 1, Solution 2 and Comparative Solution 1 shown in Table 1 above, the adsorption amount of polylysine on contact lenses was investigated. In this example, the fourth group lens "Shuabyu-" (manufactured by Johnson End Johnson Corporation) was used. For a single treatment, the lenses were immersed in 4 ml of each solution, and left to stand in Solution 1 and Solution 2 at 25° C. for 24 hours, and in Comparative Solution 1 for 8 hours. The 13 treatments were to immerse the lens in 4ml of each solution, and let it stand for 4 hours at 2...

Embodiment 2

[0047] The effect of ε-polylysine on the human eye when adsorbed on contact lenses was studied. In this example, the fourth lens group "Syuabyu-" and "2ゥイ-クアキビュ-" (manufactured by Johnson End Johnson Corporation) were used. After wearing these lenses for a whole day, the lenses were removed from the eyes, and the lenses were washed with the solutions of solution 1, solution 2, solution 3 and comparative solution 1 shown in Table 1 for more than 5 seconds, and then the lenses of the left and right eyes were washed. Each was immersed in a lens case containing each solution, and left to stand overnight. The contact lenses were removed from the lens case the next morning and worn without washing. The contact lenses were worn repeatedly for 2 weeks and treated with solution 1, solution 2 or solution 3, respectively, every day. For contact lenses treated with comparative solution 1 every day, try to wear them for 2 weeks, and stop wearing them if problems arise in wearing them. T...

Embodiment 3

[0052] According to the Stand alone test specified by ISO, the disinfection effect experiment was carried out using solution 1, solution 2, solution 3, comparison solution 2 and comparison solution 3 shown in Table 1. The results are shown in Table 4.

[0053] Table 4

[0054] Units are logarithmic reduction values

[0055] bacteria

Solution 1

Solution 2

Solution 3

Comparative Solution 2

Comparative solution 3

1 hour

4 hours

1 hour

4 hours

1 hour

4 hours

1 hour

4 hours

1 hour

4 hours

golden yellow grapes

cocci

1.86

3.51

2.16

3.32

2.80

4.50

1.90

3.00

0.15

0.98

Pseudomonas aeruginosa

＞5.00

＞5.00

＞5.00

＞5.00

＞4.90

＞4.90

＞4.70

＞4.70 ...

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PUM

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Abstract

A contact lens solution containing polylysine, polyphosphoric acid and / or its salt preventing polylysine from adsorption by contact lenses, a nitrogen-containing organic antibacterial agent other than polylysine and water. Contact lenses can be washed, disinfected and preserved merely by soaking in the above solution without rubbing or rinsing before putting into eyes.

Description

technical field [0001] The present invention relates to a liquid preparation for contact lenses, and more particularly relates to a liquid preparation for contact lenses that effectively washes, disinfects, and preserves contact lenses. Background technique [0002] Generally, when a contact lens is worn in the eye, contaminants such as proteins derived from tears and lipids derived from eye fat adhere to the surface of the contact lens. Therefore, these contaminants must be removed after the contact lens is taken out of the eye. In the case of continued use of the contact lens, contamination by microorganisms adhering to the contact lens can occur during removal of the contact lens from the eye and during storage of the contact lens in the lens case. Damage to the eye can then occur when the contaminated contact lens is worn. Therefore, it is important to sterilize contact lenses prior to wearing, especially soft contact lenses must be sterilized. [0003] Disinfection me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L12/08A61L12/14C11D3/00C11D3/37C11D3/48C11D7/16C11D7/32
CPCC11D7/3245C11D3/3719C11D3/0078A61L12/14C11D7/32C11D3/48C11D7/16C11D7/3272A61L12/143A61L12/142G02C13/00
Inventor 藤田正明中道千寻西村晋治梅田谦田尻大治齐藤文郎
Owner OPHTECS CORP
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