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Rupikang tablets against hyperplasia of mammary glands and preparation thereof

A technology of Rupikang and granules, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, bulk transportation, etc., can solve the problems of inability to comprehensively control product quality, low quality standards, and difficult swallowing by women, and achieve Comprehensive qualitative and quantitative control methods, improved quality standards, and comprehensive quality standards

Inactive Publication Date: 2003-11-19
毛友昌
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AI Technical Summary

Problems solved by technology

Although the medicinal materials containing volatile components are finely powdered for use in the process, if they are added in the granulation process, there will be losses during the drying process. Some medicinal materials containing volatile components will be lost during the decoction process, which will inevitably affect the curative effect.
Tablets are easy to produce and carry, but the dosage of the tablets is relatively large, and it is difficult for women to swallow them, and the quality standards for controlling product quality are still low, making it impossible to fully control product quality
Based on the shortcomings of tablets that affect quality, we use modern pharmaceutical technology to make necessary improvements to the product process and form new preparations to ensure product quality control, improve drug efficacy, and benefit the people.

Method used

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Embodiment Construction

[0026] The best embodiment of the invention: cleanly select the eight medicinal herbs respectively, remove impurities, and pass the inspection for later use; take 500g of Danshen and 500g of Cyperi, mix and pulverize them into fine powder, and grind the remaining Danshen, Cyperi and the remaining six flavors into coarse powder, add water and cook 2-3 times, 2-3 hours each time, collect volatile oil and water cooking liquid for later use; add appropriate amount of cyclodextrin to the above-mentioned volatile oil to synthesize volatile oil cyclodextrin inclusion compound for later use; water cooking liquid is concentrated to a relative density of 1.05-1.15 ( 60°C) concentrate, spray-dry, collect dry cream powder / concentrate into a thick paste with a relative density of 1.20-1.40 (60°C), add appropriate amount of excipients, mix well, granulate, dry, add volatile oil cyclodextrin inclusion compound , mixing, packaging, quality inspection, packaging, that is.

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Abstract

A process for preparing Chinese medicine "Rupikang particles" for treating mastoplasia and breast sweeling includes such steps as pulverizing the mixture of partial red sage root and partial cyperus tuber, decocting the rest of them along with 6 Chinese-medicinal materials for collecting volatile oil, mixing volatile oil with cyclodextrin, concentrating the decoction, drying, adding additive, mixing and together and granulating.

Description

technical field [0001] The invention relates to the technical field of preparation of Chinese patent medicine granules, in particular to Rupikang granules and a preparation method thereof. Background technique [0002] Granules are a form of traditional Chinese medicine. According to the relevant drug laws and regulations of our country, changing the dosage form is regarded as a new drug research. The original dosage form has been Rupikang Tablets, which has been included in the national standard compilation of Chinese patent medicines of the State Drug Administration-local standards of Chinese patent medicines Ascended in the "Surgical Volume" of the national standard part, it is composed of eight traditional Chinese medicines. The process of the original dosage form is as follows: part of it is powdered, part of it is made into water decoction, and appropriate amount of auxiliary materials are added, mixed, granulated, dried, compressed into tablet...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61P15/14
Inventor 毛友昌毛晓敏
Owner 毛友昌
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