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Kakonein eye drops

A technology of puerarin and eye drops, applied in the directions of organic active ingredients, sensory diseases, medical preparations containing active ingredients, etc., can solve the problems of visual function decline, poor nutritional supply, lowering IOP, etc., and reduce intraocular pressure. , Improve microcirculation and increase blood flow supply

Inactive Publication Date: 2003-06-18
浙江平湖莎普爱思制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The reason is that while reducing IOP, these drugs can also reduce the blood flow of visual organs such as the retina and cause poor nutrient supply, thereby reducing visual function.
Like timolol eye drops in the treatment, there will also be side effects of slowing down the heart rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0007] Embodiment 1: in 1000 milliliters of puerarin eye drops, the percentage by weight of contained each composition is: puerarin 0.5%, polyvinylpyrrolidone 8%, edetate disodium 0.1%, sodium metabisulfite 0.1%, 0.01% benzalkonium bromide, 6% sodium chloride, appropriate amount of sodium hydroxide, and distilled water as the rest.

[0008] Appropriate amount of sodium hydroxide means: by adding dropwise 1M sodium hydroxide solution, the pH value of the prepared solution is suitable for ophthalmic solution. 1M sodium hydroxide solution is prepared in advance, and 1M sodium hydroxide solution means that there is 1 mole of sodium hydroxide in every liter of solution.

[0009] The preparation method in this embodiment is: 1) After preparing puerarin, polyvinylpyrrolidone, disodium edetate, and sodium metabisulfite in corresponding percentages, add an appropriate amount of sodium chloride, dissolve it in distilled water, and make it It is completely dissolved; 2) Use 1M sodium hy...

Embodiment 2

[0010] Embodiment 2: in 1000 milliliters of puerarin eye drops, the percentage by weight of each composition that contains is: puerarin 1%, p-aminobenzoic acid 5%, edetate disodium 0.05%, sodium thiosulfate 0.2% %, 0.01% thimerosal, 5% borate, an appropriate amount of 2% sodium bicarbonate, and the rest is distilled water.

Embodiment 3

[0011] Embodiment 3: in 1000 milliliters of puerarin eye drops, the percentage by weight of each composition that contains is: puerarin 1.5%, polyvinyl alcohol 6%, edetate disodium 0.1%, sodium citrate 0.2% , 0.1% phenylethyl alcohol, an appropriate amount of 5% sodium chloride borate buffer solution, and the rest is distilled water.

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PUM

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Abstract

An eyedrops of kakonein for preventing and treating glaucoma contains kakonein, cosolvent, antioxidizing agent, metal complex, osmotic pressure regulator, antiseptic, pH regulator, and distilled water. Its advantages are high curative effect, low by-effect, and protecting vision.

Description

technical field [0001] The invention belongs to the field of medicines, in particular to a puerarin eye drop. Background technique [0002] Glaucoma is one of the common geriatric diseases, and about 2% of people over the age of 40 suffer from this disease. With the aging of the population, the incidence rate increases year by year. Although glaucoma can be treated surgically, drug prevention and treatment is still one of the important means. Some glaucoma drugs currently on the market usually only lower intraocular pressure (IOP). Therefore, after the patient is given the drug, although symptoms such as headache are alleviated due to the reduction of IOP, the visual acuity continues to decline. The reason is that while reducing IOP, these drugs can also reduce the blood flow of the retina and other visual organs, resulting in poor nutrient supply, thereby reducing visual function. Like timolol eye drops in the treatment, there will be a side effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61P27/06
Inventor 陈德康任宝华
Owner 浙江平湖莎普爱思制药有限公司
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