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Chinese medicine prepn. for treating coronary heart disease and angina pactoris and its prepn. process

Inactive Publication Date: 2002-10-23
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above clinical prescriptions and Chinese patent medicines all have certain deficiencies, such as invigorating qi, invigorating yang, invigorating blood, or emphasizing deficiency of both qi and yin, or poor dosage forms, and have not been fully promoted clinically.
In addition, Compound Danshen Tablets (Chinese Pharmacopoeia 77th edition, 85th edition, 95th edition and 2000 edition) have a long history of application, but the clinical effect is not satisfactory, the onset of action is slow, and the effect is poor.
Compound Danshen dripping pills (Chinese Pharmacopoeia 2000 edition one, patent application number 01136155.7) is composed of Danshen, Panax notoginseng, and Borneol. Certain curative effect, but mainly in Qi stagnation and blood stasis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Get Astragalus 86.5g (65.6%), Salvia miltiorrhiza 21.3g (16.1%), Radix Notoginseng 3.5g (2.7%), Dalbergia 20.6g (15.6%), auxiliary material polyethylene glycol-6000 30g; Panax notoginseng, decoct twice, add 7 times the amount of water each time, 2 hours each time, combine the decoction liquid, filter, concentrate the filtrate to 900ml, add 95% ethanol to make the alcohol concentration reach 70%, let it stand for 12 ~24 hours, filter, recover ethanol, concentrate into extract with relative density of 1.32~1.38 (50~60°C);

[0041] Add water to decoct the crushed Astragalus membranaceus twice, add 6 times the amount of water each time, extract for 2 hours and 1 hour in turn, combine the filtrate, and when it is concentrated to about 1500ml, add 95% ethanol to make the alcohol concentration 60%, let it stand After 12-24 hours, filter, recover ethanol from the filtrate, concentrate to about 400ml, add 95% ethanol to make the alcohol concentration 80%, let it stand for 12-24 ...

Embodiment 2

[0044] Get Radix Astragali 40.6g (30.0%), Salvia Miltiorrhiza 44.8g (33.1%), Panax notoginseng 11.2g (8.3%), Radix Dalbergia 38.6g (28.6%), make traditional Chinese medicine preparation of the present invention by conventional tablet preparation method.

Embodiment 3

[0046] Take 77.3g (57.1%) of Radix Astragali, 22.8g (16.8%) of Salvia Miltiorrhiza, 4.8g (3.6%) of Radix Notoginseng, 30.5g (22.5%) of Dalbergia, and 28g of polyethylene glycol-6000 as an auxiliary material. The preparation technology of embodiment 1 is made Chinese medicine preparation of the present invention.

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PUM

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Abstract

This invention discloses a Chinese medicine for treating coronary disease angina pectoris and it's preparation method. Said medicine comprises (wt.%) Astragalus mongholicus 22.2-66.8%, Saliva miltiorrhiza Bge 11.6-33.4%, pseudo-ginseng 2.5-13.5% and Jiangxiang 14.5-44.3%. The preparation process includes taking Saliva miltiorrhiza Bge and pseudo-ginseng to make extract paste, taking Astragalus mongholicus to make extract paste, then taking Jiangxiang to make back-flow extraction and collect volatile oil, uniformly mixing said two extract pastes and the volatile oil and proper supplementary material to obtain the invented medicine which has special curative effect to qi-asthenia blood-stasis type coronary disease.

Description

technical field [0001] The present invention relates to a kind of medical preparation, more specifically, relates to a kind of traditional Chinese medicine preparation. Background technique [0002] Coronary heart disease is a common disease, and it is also one of the diseases that seriously harm the middle-aged and elderly people. In recent years, due to social development, changes in work, life, diet and environment, the number of patients with coronary heart disease is on the rise. According to relevant statistics, the incidence rate of coronary heart disease patients over middle age is 2.47%-3.18%. At present, the western medicines for treating coronary heart disease are mainly nitrate compounds, beta-receptor blockers and calcium antagonists, etc. These medicines can only relieve symptoms, but are difficult to cure the root cause, and have certain toxic and side effects. Although the single-target effect of traditional Chinese medicine is low...

Claims

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Application Information

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IPC IPC(8): A61P9/10
Inventor 阎希军吴迺峰郭治昕叶正良张文生高鹏
Owner TIANJIN TASLY PHARMA CO LTD
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