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Pressure sensitive adhesive composition

A technology of adhesives and compositions, applied in the field of pressure-sensitive adhesive compositions, wound dressings or ostomy devices, which can solve the problems of limiting the integrity of swelling adhesives

Inactive Publication Date: 2002-04-17
COLOPLAST AS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the lack of a gel that sticks together, the cross-linked hydrocolloid can leach out and become suspended in body fluids, thereby limiting the effect on the integrity of the swelling adhesive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] A binder material according to the invention comprising PIB and having the components listed in Table 1 below was prepared:

[0064] Element

weight percent

PIB

40

amidated pectin

27.5

Potato starch

5

CMC

27.5

[0065] 80 grams of PIB were added to the Z-blender at 80°C and softened under 50 mbar vacuum for about 10 minutes. The vacuum was then released and 55 grams of amidated pectin, 55 grams of CMC and 10 grams of potato starch were added and mixed for 15 minutes, mixing continued under 50 mbar vacuum until a homogeneous dough-like mass was formed.

[0066] The dough-like mass is then removed from the mixer while hot and soft and made by compression molding the binder mass between two sheets of silicon paper at about 90°C and 100 bar. A sheet stock about 1 mm thick is formed. The resulting slabs were cut into desired shapes.

Embodiment 2-4

[0068] Binder compositions of the present invention (Tables 2 and 3) were prepared in a manner similar to that disclosed in Example 1 with the components listed in the weight percents in Table 2 below:

[0069] Element

Embodiment 5

[0071] A binder material according to the invention was prepared comprising PIB and SIS and having the components listed in Table 3 below:

[0072] Element

weight percent

PIB

40

Kraton D1107(SIS)

10

Zinc oxide

3

amidated pectin

16

Potato starch

15

CMC

16

[0073] 100 grams of PIB was added to the Z-blender at 150°C and softened for 5 minutes. 100 grams of Kraton were then added and mixing continued at 150°C and 50 mbar until the blend was homogeneous. The material was cooled to 80°C. 160 grams of material were removed from the mixer and 60 grams of PIB, 6 grams of zinc oxide, 32 grams of amidated pectin, 30 grams of potato starch and 32 grams of CMC were added to the mixer. Mixing was continued at 80° C. and 50 mbar until a homogeneous dough-like mixture was obtained.

[0074] The dough-like mass is then removed from the mixer while hot and soft and made by compr...

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PUM

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Abstract

A pressure sensitive adhesive composition suitable for medical purposes comprising a rubbery elastomeric base and two or more water soluble or water swellable hydrocolloids, said adhesive composition comprising a substantially homogeneous mixture of 15-60 % of one or more rubbery components, 10-60 % of a mixture of hydrocolloids comprising one or more hydrocolloids selected from the group of amidated pectins and potato starch, 0-50 % of one or more tackifier resins, 0-15 % cohesive strengthening agent, 0-10 % of a plasticizer and 0-5 % pigment, shows at least as good properties with respect to resistance to biological fluids as well as adhesion to the skin and coherence as state of the art adhesives comprising gelatine.

Description

field of invention [0001] The present invention relates to pressure sensitive adhesive compositions suitable for various medical applications, especially for adhesion to the skin, especially in the field of ostomy care. More specifically, the present invention relates to an adhesive composition comprising a rubbery elastic substrate and two or more water-soluble or water-swellable hydrocolloids dispersed in the substrate, which adhesive composition is used in the preparation of Use in wound dressings or adhesive sheets for ostomy appliances, and wound dressings or ostomy appliances comprising such an adhesive composition and a hydrocolloid mixture. Background of the invention [0002] In many cases, a consequence of surgery associated with mass disease of the gastrointestinal tract is that the colon, ileum, or urethra are surgically exposed, the patient's abdomen opens, and bodily effluents or waste products transported through these organs pass through a stoma or The holes...

Claims

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Application Information

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IPC IPC(8): A61F13/00A61L15/16A61L15/58A61L28/00C09J7/02C09J103/02C09J103/14C09J121/00
CPCA61L28/0019A61L28/0026Y10T428/2865Y10T428/2852Y10T428/2857Y10T428/2861
Inventor R·瓦本盖德D·乔克
Owner COLOPLAST AS
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