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Compound stemona cough stopping medicine and its preparation method

A cough medicine, Baibu technology, applied in the field of compound Baibu cough medicine and its preparation, can solve the problems of large dosage of granules, easy moisture absorption and caking of granules, and achieve good taste and elegant appearance , quality controllable effect

Active Publication Date: 2007-08-15
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage is that the preparation is a granule, the dosage form is relatively backward, the dosage of the granule is large, and the granule contains a large amount of sucrose; the granule is easy to absorb moisture, and it is prone to agglomeration during storage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1. A kind of compound Baibu antitussive medicine, it is the medicament that is made by the raw material of following weight content, and described medicament dosage form is effervescent tablet, (unit: gram),

[0051] Raw materials of Chinese herbal medicine:

[0052] Baibu (Honey Roast) 100 Bitter Almond 50 Platycodon 50

[0053] Morus alba 50 Ophiopogon japonicus 25 Anemarrhena 25

[0054] Scutellaria baicalensis 100 Tangerine peel 100 Licorice 25

[0055] Araceae (made) 25 Citrus aurantium (stir-fried) 50;

[0056] medical supplements:

[0057] Citric acid 80 Macrogol 6000 20 Sodium bicarbonate 80.

Embodiment 2

[0058] Example 2. The preparation method of a kind of compound Baibu antitussive medicine described in embodiment 1, its steps are as follows:

[0059] (1) Take the 11 Chinese herbal medicine raw materials, add 10 times the amount and 8 times the amount of water to decoct twice, each time for 2 hours, combine the decoction, filter, and decompress the filtrate under the condition of -0.09MPa and 80°C Concentrate until a clear paste with a relative density of 1.35 measured at 50°C is obtained, then vacuum-dried below 70°C, crushed into fine powder, added fine powder of citric acid, mixed evenly, granulated with absolute ethanol, and dried; Separately take polyethylene glycol 6000 and dissolve it in absolute ethanol, add sodium bicarbonate, make granules, and dry;

[0060] (2) Mix the above two dried granules evenly, add appropriate amount of cyclamate and essence, and press into 100 tablets to obtain the finished compound Baibu Zhike effervescent tablet.

Embodiment 3

[0061] Example 3. A kind of compound Baibu antitussive medicine, it is the medicament that is made of the raw material of following percentage by weight content, and described medicament dosage form is effervescent tablet,

[0062] Raw materials of Chinese herbal medicine:

[0063] Honey Roasted Beetroot 13% Bitter Almond 6.5% Bellflower 6.5%

[0064] Morus alba 6.5%, Ophiopogon japonicus 3% Anemarrhena 3%

[0065] Skullcap 13% Tangerine Peel 13% Licorice 3%

[0066] Araceae 3% Stir-fried Fructus Aurantii 6.5%;

[0067] medical supplements:

[0068] Fumaric Acid 10% Macrogol 6000 3% Sodium Bicarbonate 10%.

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PUM

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Abstract

A Chinese medicine in the form of effervescent tablet for treating cough is prepared from 11 Chinese-medicinal materials including bitter almond, mulberry bark, tangerine peel, liquorice root, etc and 3 medicinal additives: citric acid, dicarbonate and polyethanediol 6000.

Description

technical field [0001] The invention relates to a medicine made from Chinese herbal medicine, in particular to a compound Baibu cough medicine; the invention also relates to a preparation method of the medicine. Background technique [0002] In the prior art, Compound Baibu Zhike Granule is a classic Chinese patent medicine. It is made into granules of 11 medicines, such as honey-roasted Baibu, bitter almond, platycodon, mulberry root, Ophiopogon japonicus, Zhimu, scutellaria baicalensis, tangerine peel, licorice, arachis, fried aurantium citrus, etc. -20 grams, 2-3 times a day, reduce it for children. 10 grams per bag, equivalent to 6 grams of raw medicinal materials. The compound Baibu Zhike granule has the effect of clearing the lung and relieving cough, and is used for the clinical treatment of cough due to lung heat, yellow and sticky phlegm, and pertussis. Its defect is that the preparation is a granule, the dosage form is relatively backward, the dosage of the gran...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61K36/8968A61K36/8964A61K36/8884A61K36/752A61K36/75A61K36/736A61K36/605A61K36/539A61K36/484A61K36/34A61K9/20A61K9/46A61P11/14
Inventor 肖伟戴翔翎凌娅张辉尚强王振中
Owner JIANGSU KANION PHARMA CO LTD
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