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Making process of medical fiber

A manufacturing method and fiber technology, which are applied in the field of biomaterial fiber manufacturing, can solve the problems of long recovery time, excessive fiber degradation, and inapplicability, and achieve the effects of simple processing and wide source of raw materials.

Inactive Publication Date: 2005-09-28
DONGHUA UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The healing time of different surgical parts is different in the operation. In the parts that take a long time to heal, the existing surgical sutures and medical accessories made of medical fibers are not suitable.
Because it takes a long time to recover, the fiber degrades too fast, which is not good for wound healing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] Embodiment 1. Select the raw material of beta-hydroxybutyric acid and beta-hydroxyvaleric acid copolymer (abbreviated as PHBV) whose number average molecular weight is 240000, through drying, adopt the method that melt extrusion combines with wet molding, control melt temperature Spin PHBV as-spun fibers at 182°C at a spinning speed of 800m / min. After the as-spun fibers are stretched 4 times, they are set in a sizing box at 80°C for 1 hour to obtain PHBV finished fibers. The fineness of the finished fiber is 64 dtex, the breaking strength is 2.1 cN / dtex, and the breaking elongation is 42%.

Embodiment 2

[0009] Embodiment 2. Select the raw material of beta-hydroxybutyric acid and beta-hydroxyvaleric acid copolymer (abbreviated as PHBV) whose number average molecular weight is 700000, through drying, adopt the method that melt extrusion combines with wet molding, control melt temperature PHBV as-spun fibers were spun at 240°C at a spinning speed of 3000m / min. After the as-spun fibers were stretched 1.95 times, they were set in a sizing box at 150°C for 72 hours to obtain PHBV finished fibers. The fineness of the finished fiber is 3dtex, the breaking strength is 4.2cN / dtex, and the breaking elongation is 80%.

Embodiment 3

[0010] Embodiment 3. Select the raw material of beta-hydroxybutyric acid and beta-hydroxyvaleric acid copolymer (abbreviated as PHBV) whose number average molecular weight is 50000, through drying, adopt the method that melt extrusion combines with wet molding, control melt temperature PHBV as-spun fibers were spun at 170°C at a spinning speed of 400m / min. After the as-spun fibers were stretched 8 times, they were set in a sizing box at 50°C for 36 hours to obtain PHBV finished fibers. The fineness of the finished fiber is 80 dtex, the breaking strength is 1.5 cN / dtex, and the breaking elongation is 57%.

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PUM

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Abstract

The production method of medical fibre uses beta-hydroxybutyric acid and beta-hydroxyvaleric acid as raw material, and adopts the following steps: drying, melting, extruding, conveying, metering and spraying, cooling, solidifying and forming, drawing and setting to obtain the invented finished product. Said invented medical fibre possesses long degradation time, can be used for making operative suture and medical auxiliary material for curing wound hard to healing.

Description

technical field [0001] The invention relates to a method for manufacturing biomaterial fibers, in particular to a method for manufacturing medical fibers that can be absorbed by the human body. Background technique [0002] At present, the medical fibers used to make surgical sutures and medical accessories mostly use glycolide-lactide copolymers or chitin as raw materials, and are made by wet and dry methods. The fiber made of this raw material has a large drop in wet strength and a short degradation time. Generally, its strength drops by about 50% in one week. And in the operation, the healing time of different operation parts is different, and in the position that takes a long time to heal, the surgical sutures and medical auxiliary materials that existing medical fibers are made are just not applicable. Because it takes a long time to recover, the fiber degrades too fast, which is not good for wound healing. Contents of the invention [0003] The purpose of the prese...

Claims

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Application Information

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IPC IPC(8): A61L33/00D01F6/00
Inventor 陈彦模朱美芳张瑜吴文华闫卫东陈学军李佳灵
Owner DONGHUA UNIV
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