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Human body implant material and preparation method thereof

An implant material and human body technology, applied in the field of medical devices, can solve the problems of inability to form bony fusion, poor osteogenic performance, loose PEEK implants, etc., and achieve good osteoinductive ability and excellent mechanical properties

Pending Publication Date: 2022-07-26
西安卓恰新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, PEEK is a biologically inert material with poor osteogenic performance and cannot form bony fusion; after implanted into the human body, a fibrous boundary membrane is easily formed between the PEEK material and the tissue, resulting in the loosening or even prolapse of the PEEK implant, which seriously hinders the It is widely used in clinic as a medical implant material
[0003] Fiber-reinforced modified polyether ether ketone material is the most commonly used method, for example, the domestic patent "Preparation method of a special skeleton material of polyether ether ketone rubber" (publication number CN 110804275 A) and the domestic patent "A high wear-resistant Self-lubricating Orthopedic Implant Articular Surface Friction Pair" (Publication No. CN 110115778 A) uses glass fibers and carbon fibers to modify PEEK materials respectively. Although it can improve the mechanical properties of PEEK, it does not mention whether it can improve PEEK biological activity

Method used

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  • Human body implant material and preparation method thereof
  • Human body implant material and preparation method thereof
  • Human body implant material and preparation method thereof

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Effect test

Embodiment 1

[0037] In this embodiment, the human implant material in the present invention needs to be prepared into a PEEK bone plate. In this embodiment, magnesium alloy is used as the material of the additive 1, and PEEK (450PF) is used as the material of the main body 2. The preparation method of this embodiment is as follows:

[0038] A) Raw material pretreatment: The PEEK (450PF) particles are dried in a vacuum drying oven at a temperature of 160° C. for 24 hours to obtain dried PEEK (450PF) particles; the magnesium alloy material is processed into magnesium fibers with a length of 2 mm and a diameter of 100 μm , and then put the magnesium fiber into a beaker filled with acetone solution for ultrasonic cleaning, the cleaning time is 10min, the surface impurities are washed away, and then washed with distilled water three times and dried.

[0039] B) Weigh 200 g of dried PEEK (450PF) particles and 40 g of dried magnesium fibers, put them into the extruder of SJZS-10B, and connect the...

Embodiment 2

[0043] In this embodiment, the raw material of additive 1 is magnesium fiber with a length of 5 mm, a diameter of 100 μm and a mass of 50 g, and other operation steps are the same as those in the first embodiment.

[0044] In the human implant material in this embodiment, the mass percentage of Additive 1 is 20%. like figure 2 As shown, the mechanical properties of this embodiment are better than those of pure PEEK material, and also better than the first embodiment.

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Abstract

The invention relates to a human body implant material and a preparation method, the human body implant material comprises a main body and an additive, the main body is made of PEEK (polyetheretherketone), the additive is made of magnesium or magnesium alloy, and the additive is partially exposed on the surface of the main body. The preparation method of the human body implant material comprises the steps of raw material pretreatment, raw material mixing and cooling molding. The human body implant material provided by the invention has excellent mechanical properties and good bone induction ability.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a human implant material and a preparation method. Background technique [0002] Traditional orthopedic metal materials, such as titanium and its alloys, have an excessively high elastic modulus, which can cause a “stress shielding” effect, resulting in bone resorption and bone atrophy around the implant, causing great pain in the patient and leading to implant failure. PEEK (polyetheretherketone) is a new type of organic polymer material with strong stability and good mechanical compatibility. Its elastic modulus is similar to that of bone and will not cause bone resorption and interface loosening. However, PEEK is a biologically inert material with poor osteogenic properties and cannot form bony fusion; after implantation into the human body, a fibrous limiting membrane is easily formed between the PEEK material and the tissue, resulting in the loosening or even prolapse of the P...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06A61L31/14A61L31/02A61L31/16
CPCA61L31/06A61L31/14A61L31/022A61L31/16A61L2300/102A61L2300/412C08L61/16
Inventor 高敏宫海波肖杰
Owner 西安卓恰新材料科技有限公司
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